Biodistribution of RadioPharmaceuticals in Nuclear Medicine

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6 Terms

1
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What is Biodistribution?

The distribution of a radiopharmaceutical within the body over time.

2
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What is biodistribution influenced by?

  • Molecular structure

  • Route of administration

  • Organ perfusion

  • Transport mechanism

  • Metabolism and excretion

3
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What is pharmacokinetics (PK)

What the body does to the drug

4
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What are the examples of pharmacokinetics?

  • absorption

  • metabolism

  • Excretion (ADME)

5
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What is pharmacodynamics?

What the drug does to the body

6
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What are the examples of pharmacodynamics?

  • receptor interactions

  • localization

  • biological effects