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What is Biodistribution?
The distribution of a radiopharmaceutical within the body over time.
What is biodistribution influenced by?
Molecular structure
Route of administration
Organ perfusion
Transport mechanism
Metabolism and excretion
What is pharmacokinetics (PK)
What the body does to the drug
What are the examples of pharmacokinetics?
absorption
metabolism
Excretion (ADME)
What is pharmacodynamics?
What the drug does to the body
What are the examples of pharmacodynamics?
receptor interactions
localization
biological effects