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Neurons
Specialized cells that transmit electrical impulses and translate them into chemical signals.
Soma (Cell Body)
Contains the neuron’s nucleus and maintains cell health.
Dendrites
Receive incoming messages from other neurons.
Axon Hillock
Integrates signals from the soma and determines if an action potential will be fired.
Axon
Carries electrical impulses away from the soma to other neurons, muscles, or glands.
Myelin Sheath
Fatty covering on the axon that increases the speed of neural transmission.
Nodes of Ranvier
Gaps in the myelin sheath where ion exchange occurs during impulse transmission.
Nerve Terminal
End of axon that releases neurotransmitters to communicate with other neurons.
Synaptic Cleft
Gap between presynaptic and postsynaptic neurons where neurotransmitters travel.
Synapse
The junction including presynaptic terminal, synaptic cleft, and postsynaptic membrane.
Sensory Neurons (Afferent)
Carry sensory information from receptors to the CNS.
Motor Neurons (Efferent)
Carry motor commands from the CNS to muscles and glands.
Interneurons
Connect neurons within the CNS; involved in reflexes.
Multipolar Neuron
Neuron with multiple extensions from the soma.
Bipolar Neuron
Neuron with two extensions.
Unipolar Neuron
Neuron with one extension.
Astrocytes
Glial cells that nourish neurons and form the blood-brain barrier.
Ependymal Cells
Line ventricles and produce cerebrospinal fluid (CSF).
Microglia
Phagocytic cells that remove waste and pathogens from the CNS.
Oligodendrocytes
Produce myelin in the CNS.
Schwann Cells
Produce myelin in the PNS.
Resting Potential
The difference in charge across a neuron’s membrane, typically -70mV.
Depolarization
Increase in membrane potential due to excitatory input.
Hyperpolarization
Decrease in membrane potential due to inhibitory input.
Threshold
The membrane potential (around -55mV) needed to trigger an action potential.
Repolarization
Restoration of negative membrane potential after depolarization.
Refractory Period
Period after firing when a neuron cannot fire again.
Saltatory Conduction
Jumping of action potential between nodes of Ranvier.
Neurotransmitters
Chemical messengers released from neurons to communicate across synapses.
Reuptake
Process where neurotransmitters are reabsorbed by the presynaptic neuron.
Enzymatic Degradation
Breakdown of neurotransmitters by enzymes (e.g., ACh by acetylcholinesterase).
Acetylcholine (ACh)
Enables muscle action, learning, and memory; low levels linked to Alzheimer’s.
Dopamine
Influences movement, learning, attention, emotion; excess linked to schizophrenia, low to Parkinson’s.
Serotonin
Affects mood, hunger, sleep; low levels linked to depression.
Norepinephrine
Controls alertness and arousal; low levels can depress mood.
GABA
Main inhibitory neurotransmitter; low levels cause seizures, tremors, insomnia.
Glutamate
Main excitatory neurotransmitter; oversupply causes migraines or seizures.
Endorphins
Natural painkillers and pleasure enhancers; oversupply from opioids suppresses natural production.
Agonist
Molecule that increases a neurotransmitter’s action.
Antagonist
Molecule that blocks or inhibits a neurotransmitter’s action.
Central Nervous System (CNS)
Brain and spinal cord; controls decision-making.
Peripheral Nervous System (PNS)
Connects the CNS to the body via sensory and motor neurons.
Somatic Nervous System
Controls voluntary skeletal muscle movement.
Autonomic Nervous System (ANS)
Controls involuntary functions (glands, organs).
Sympathetic Nervous System
Arouses body and expends energy (fight-or-flight).
Parasympathetic Nervous System
Calms the body and conserves energy (rest-and-digest).
Endocrine System
Glands that secrete hormones into the bloodstream.
Pituitary Gland
Master gland that controls hormone release.
Hypothalamus
Links nervous and endocrine systems; regulates hunger, thirst, temperature, and sex drive.
Cortisol
Stress hormone released by adrenal glands; increases blood sugar.
Brainstem
Central core of the brain; controls automatic survival functions.
Medulla
Regulates heartbeat and breathing.
Pons
Coordinates movement and controls sleep.
Cerebellum
“Little brain”; coordinates movement, balance, and nonverbal learning.
Reticular Formation
Filters information and controls arousal.
Thalamus
Directs sensory messages to the cortex and transmits replies to the cerebellum and medulla.
Amygdala
Processes emotions such as fear and aggression.
Hippocampus
Forms and processes conscious memories; shrinks with age.
Cerebral Cortex
Outer layer of the brain; responsible for higher thought and processing.
Frontal Lobe
Involved in movement, speaking, planning, and decision-making.
Parietal Lobe
Processes sensory information from touch and body position.
Occipital Lobe
Processes visual information.
Temporal Lobe
Processes auditory information.
Motor Cortex
Controls voluntary muscle movements.
Somatosensory Cortex
Receives sensory input from the body.
Visual Cortex
Processes visual input.
Auditory Cortex
Processes sound input.
Association Areas
Integrate information; involved in judgment, planning, and memory.
Lateralization
Specialization of brain hemispheres.
Left Hemisphere
Responsible for language and positive emotions.
Right Hemisphere
Handles spatial abilities and negative emotions.
Brain Plasticity
Brain’s ability to adapt or reorganize, especially during development.
EEG (Electroencephalogram)
Records electrical activity of the brain.
ERP (Event-Related Potential)
Measures brain response to specific stimuli.
CAT Scan
X-ray that provides detailed 2D brain images.
MRI
Uses magnetic fields to create clear 3D brain images.
DTI (Diffusion Tensor Imaging)
Measures integrity of white matter.
PET Scan
Uses radioactive tracer to show brain activity via blood flow.
fMRI
Measures brain activity by detecting oxygenated blood flow.