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epigenetic changes can be
reversible and are often influenced by the evnironment
diffentiation means the
process where step cells become specialized and epigenetics helps guide this
stem cell
undifferenciated, can form more differenciated cells
undiffrerenciated
cells taht can develop ino many specialized types
waddington-epigenetic landscape
a metaphor showing how cells “roll down” diffrent paths to become a specified cell type
enviornment during development affects
epigenome of cells like predators
Daphania and the enviornment
they grow helmets in response to predator exposure driven by epigenetic change
two types of txn factor feedback loops
lots of activator→ stays high expression
not much activator→ stays low expression
lots of activator leads to
new cells also has lots of activator the daughter cell with inherit high expression lvls
not muc activators will lead to
new cells also has not much activator low expression will get passed on
barr bodies and epigenetics
is an example of epigenetic silencing no change ot DNA just turned off
Epigenetics by CpG islands
can be passed down during cell division but more epigentic marks are wiped clean every generation so offspirngs with get it
hemimethylated
each dna molecule withll have methylationon ONE dna strand but not the strand