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Neurotransmitters
Nervous system
transmit through neural network
fast acting
effects quick but short duration
Hormones
Endocrine system
transmit through blood stream
slow acting
effects take time to begin but are long lasting
neurotransmitters are
chemical messengers in brain .
After connecting to the receiving receptor and sending the message. returns to presynaptic neuron through reuptake
2 main types of neurotransmitters
Excitatory = causes receiving cell to increase neural firing
Inhibitory = causes receiving cell to decrease neural firing
What does the neurotransmitter serotonin do
regulates mood , sleep, wakefulness, eating, and aggressive behaviors
Inhibitory
If there is not enough → Mood disorders, anxiety , insomnia, OCD
What does the neurotransmitter norepinephrine do
Fight or flight
stress arousal eating
increases attention and memory for emotionally charged events
not enough → depression
Too much → anxiety, stress, nervous tension
Excitatory
What does the neurotransmitter Acetylcholine do
Skeletal muscles contract, regulates heart muscles
transmits messages between brain and spinal cord
memory formation, learning, general intellectual functioning
not enough → low arousal and attention
alzheimer’s disease
Too much → violent muscle contractions/spasms
excitatory
What does the neurotransmitter Glutamate do
enhances transmission of info from senses to brain
deals with learning and memory
excitatory
too much → overstimulated → seizures and migraines
What does the neurotransmitter Glutamate do
Inhibitory neurotransmitter
offsets other excitatory messages
regulates sleep-wake cycle
not enough → anxiety, seizures, insomnia
too much → sleep and eating disorders
What does the neurotransmitter endorphins do
natural opiate
regulates pain perception
inhibitory
released during exercise and linked to positive emotions
too much → artificial heights
too little → feel pain
What does the neurotransmitter Dopamine do
Voluntary coordinated motor movements
attention learning memory
reward sensations
not enough → parkinson’s disease
too much → schizophrenia, bipolar, adhd
Both inhibitory and excitatory
What does the neurotransmitter Substance P do
modulation of pain
excitatory
contraction of smooth muscle and dilation of blood vessels
potent neurotransmitter especially in transmission of signals from pain receptors
What are hormones
Chemical messenger that travels through bloodstream
released by glands in the endocrine system
affects brain and other parts of the body [ growth , reproduction, metabolism, mood ]
slower transfer but effects last longer
adrenaline
increases heartbeat
fight or flight
= epinephrine
Melatonin
regulation of circadian rhythms
sleepiness
Ghrelin
released by hypothalamus
signals hunger and need to eat
Leptin
released by hypothalamus
allows you to feel full
oxytocin
stimulates contractions in childbirth; love hormone
Electroencephalography
electrical signals from brain ( neurotransmission )
strength : shows level of activity and speed
Weakness : does not show what part of the brain ats this way
Ex: sleep studies
Positron emission Tomography
shows glucose absorption or blood flow in the brain
where it is being absorbed in an active brain ( radioactive glucose is being tracked )
PET color codes are based on consumption rates
Weakness : less precise than fMRI, uses radiation
ex: brain activity difference s
functional magnetic resonance imaging
magnet measures change in blood flow and creates 3d image
slices of brain in specific detail and location of activity
ex: searching for abnormalities and lesions
lesion = disruption or damage to tissue
Heritability
proportion of variabtion among individuals that we can attribute to ourgenes
interaction
impact of one factor depends on another factor ( genes affect how people react to and influence us )
epigenetics
study of how n environment can later or influence genetics and genetics expression
monozygotic
identical
dizygotic
fraternal
Twin similarity breakdown
most similar = identical and raised together
2nd = idental and raised apart
3rd = fraternal and raised together
Nervous Systems breakdown
Central nervous system [ brain and spinal cord . spinal cord connects brain with peripheral nervous system , decision making portion ]
Peripheral NS [ motor and sensory neurons that receive information and transmit central nervous system decisions ]
somatic ns = voluntary control of skeletal muscles
autonomic NS = functions of gland and internal organ muscles
sympathetic NS = fight or flight, dilates pupils, speeds breathing, relaxes bladder
Parasympathetic NS = slows down, increases digest
Neuron
nerve cell and basic building block of the nervous system . Bundle of axons and link the central NS with the body’s receptors, muscles, and glands
Types of Neurons
Sensory
Receive information from outside world and sends to the brain via the spinal cord ( afferent neurons )
Motor
Carry signal from the spinal cord to the muscles and glands ( effeerent )
Interneurons
connect sensory and motor neurons toge3ther
found in the brain and spinal cord
Parts of the neuron
Dendrite, cell body/some, axon, myelin sheaths, axon terminal, terminal buttons, synapse, receptor
Dendrite = recieves messages from neighboring cells
Cell body/soma =neurons life support center, indicates whether to continue message or not
axon = passes messages away from cell body to neighboring neurons, muscles, and glands
myelin sheath = covers up some axons to protect and speed up neutral signal
axon terminal = end of axon that leads to neighboring cells to send message
terminal buttons = end of axon terminal where neurotransmitters are stored and released to send message
synapse = junction between sending and receiving neurons; synaptic gap where neurotransmitters are released
Receptor = cell on dendrites that Neurotransmitters connect to in order to send message to next neuron and start process over
after NT connects, the excess will be reabsorbed by the sending neuron ,called reuptake
Action potential
neural impulse or a brief electrical charge that travels down an axon
triggered by an electrical shock that is above the cells treshold
all or nothing principle = no varying levels of action potential- it either fires ta the same level or does it
Refractory period
time it takes to recover from one action potential
Steps of action potential
Resting potential
Threshold passed
voltage rises = depolarization
Voltage falls - repolarization
refractory period
Glial cells are
non neuron cell in the nervous system that provides support, protection, and nourishment of neurons
insulation for axons and myelin , communication, and waste transport ( removes used neurotransmitters )
glue that hold neural network together
outnumbers neurons
also plays a role in learning thinking and memory
The degeneration of myelin sheath →
slows communication to muscles and brain regions → multiple sclerosis
Agonists effect on neurons
increae actions of NT ,
either by increasing production or releae of NT
blocks reuptake ( stays in synapes longer )
mimicsthe NT effects
Antagonists effect on neurons
decrease NT action by blocking production or release of neutrosansmittors or block receptor sites
Reuptake inhibitor effect on neurons
block the reabsorption of NT back into sending neuron
ex: antidepressents partially block the reuptake of mood -enhancing NT , making it stay in the synaptic gap longer and increasing its effects ( selective serotonin reuptake inhibitors )
Depressants
Drugs that reduce neural activity and slow body functions
Ex: Alsochoo, opiods, tranquilizers
Stimulants
Drugs that excite neural activity and speed up body functions
ex: cocaine, Caffeine, Nicotine, Ectasy
Hallucinogens
Psychedelic drugs that distort perception and evoke sensory images in absense of sensory input
ex: LSD , ecstasy, marijuana
Opioids
Opium and its Derivatives, depress neural activity, temporarily lessening pain and anxiety
ex: heroin, fentanyl