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Fredrich Meischer
Discovered nuclein (DNA) in pus cells from bandages in 1869. First person to identify DNA as a unique substance in cells
Franklin and Wilkins
Used X-ray diffraction to study DNA’s structure. Franklin’s famous photo 51 showed Dna’s double helix structure, helping watson and crick
Beadle and Tatum
Proposed “one gene-one enzyme” hypothesis, showing genes control the production of specific enzymes. Worked with mold
Watson and Crick
Built the first accurate model of DNA’s double helix in 1953, showing how base pairing allows DNA replication
Frederick Griffith
DDiscovered bacterial transformation in 1928. Harmless bacteria became deadly when mixed with heat-killed deadly bacteria.
Meselson and Stahl
Proved that DNA replication is semi-conservative (new strand +old strand) using nitrogen isotopes.
Avery, MacLeod, McCarty
Showed that DNA is the transforming principle (not protein) in bacteria. Confirmed griffiths findings ion 1944
Chargaff
Discovered base pairing rules in DNA, establishing that A=T and C=G. (chargaffs rules)