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Cardiovascular system
Transport system that carries nutrients, waste & other important chemicals throughout the body
Heart
A pump that has 4 chambers & 2 stroke pumps
a hallow bag of muscle
Myocardium
Thickest part of the heart
contracts to shrink chambers of the heart to pump blood
Surrounds by pericardium tissue that protects and anchors the heart muscles to surrounding tissues
Right atrium
Collecting chamber that first collects blood returning from the body and pumps it to the right ventricle
Blood returns to the right atrium from these 3 vessels
Superior vena cava: upper part of the body
Inferior vena cava: lower part of the body
Cardiac sinus: coronary arteries (within the heart)
Left atrium
Collects blood returning from the lungs via pulmonary vein and pups blood to left ventricle
Right ventricle
Pumps blood to lungs via the pulmonary artery
Left ventricle
Pumps blood to the whole body through the aorta
Valves
Prevent backdown of the blood in your heart
the valves between the atria and ventricles are the Tricuspid (right) and Bicuspid (left) mitral valves
Valves between the ventricles and vessels are the semilunar valves (aortic and pulmonary)
Pulmonary circulation
Starts from the right side of the heart and de-oxygenated blood travels to the lungs to gain O2 & deposit CO2 and returns to the left side of the heart oxygenated
Systemic circulation
Starts on the left side and the oxygenated blood travels to the organs & returns the de-oxygenated blood to the right side of the heart
Electric control
heartbeat is firstly controlled by brain stem
Heart is a muscle - cells are similar to the skeletal muscle but electrically connected
When gets signalled to contract they all will contract(all or nothing principle)
Sino-atrial node
Bundle of nerve cells in the walls of the right atrium causing the heart to beat intrinsically @ ~75bpm
heart’s natural pacemaker
Atrio-ventricular node
Bundle of nerve cells in the walls between the right atrium & right ventricle that are meant to delay electrical signals to ventricles by 0.1 seconds
So everything gets into ventricle front he atria before being sent away
Second job is to take over for the SA node if needed
Blood Pressure
A measure of force with which blood pushes on the walls of the aorta & other arteries
tidal measurement as pressure & flow of blood changes between contraction phase (rapid & strong flow) & relaxation phase (slower & more gentle flow) of heart muscles
Normal/healthy BP is 120/80mm of Mercury
High BP is expected & normal especially during exercise because the heart pumps faster & with greater force because the body is demanding more
Systole
Period of strongest contraction of ventricles - highest pressure of blood in aorta
Diastole
Period of relaxation of ventricle - lowest pressure in aorta
Blood Pressure formula
Systole/diastole
Heart rate
Average measure for how many times heart contracts/“beats” in 1 min
avg resting HR is 75bpm
HR increases during exercise to meet body’s demand
Stroke volume
Amount of blood pumped by each “stroke” of the left ventricle
measured in ml/beat
Varies per person based on their gender & size
Cardiac output
Amount of blood pumped by a ventricle in 1 minute
CO = HR x SV
Avg body has a total blood volume of 5L, so entire volume of blood will circulate completely around body each minute
Arteries
Transports blood away from the heart
systemic arteries always carry oxygenated blood
Pulmonary artery’s carry deoxygenated blood there is high pressure of blood in the arteries
Al starts from the aorta that has the largest and greatest pressure
Branches & its diameter decreases until the smallest arteries (arterioles)
Thick & have small muscles
Muscles can change diameter of artery
Act as a secondary pump
Vasodilation
Blood flow increases because the diameter increases
Vasoconstriction
Blood flow decreases because diameter decreases
Capillaries
Smallest vessels in the body & could have the thickness of a RBC
there are lots of capillaries in the body
Very very thin walls
Site of material exchange between the blood and the tissues
Forms a 3-d web of the body
Gases and small solutes pass through the walls while the larger materials pass through the pores
Veins
Carries blood back to the heart
mostly carries deoxygenated blood
Except for the pulmonary vein that carries oxygenated blood
Has no muscles and has low pressure
Veins have one way valves that prevent back flow
Venus return
Mechanism helping blood flow back into the heart
Muscular pump
Veins often located along the outside of muscles & when the muscle contracts it squeezes the veins resulting in the pumping action
Thoracic pump
Diaphragm moves up and down causing breathing and as it does that it creates an alternating sequence of pressure change in the body cavity & causes veins to expand & contract causing the pumping action
Blood
Main vehicle of transport in the body
Plasma
Is found within blood and is a clear fluid that is ~55% of blood volume that carries all dissolved solutes
mostly water
Salts, sugars, gases, various biochemicals
Blood cells
~45% blood volume
~2% of cells are either
leukocytes: WBC
Immune system
Thrombocytes: platelets
Clotting
99% of blood cels are
erythrocytes: RBC
Round donut shaped and is flat
Produced in the bone marrow of long bones
Lives for ~120 days
Hemoglobin
Carries O2 around the body
bodyguard
Starts out blue/green until it binds with O2 making is oxyhemoglobin (red) and when it unbinds it becomes blue/green again
Anemia
When you don’t have enough RBC (iron)
Sickle Cell disease
Poorly shaped blood cells
Blood popping
Taking blood out & putting it back in
erythropotin: stimulates RBC production
Carbon monoxide poisoning
CO is better 2 binding to hemoglobin than O2
CO2 transport
80% of CO2 is dissolved in plasma
Reacts wth H2O to make HCO3 → bicarbonate
Bicarbonate solution is a buffer for blood pH (7.4)