BIOL 2083 Chapter 21: ATP Synthesis

False

True or False: ATP synthase makes ATP via substrate-level phosphorylation

C. bacteriorhodopsin

What protein was used in the experiment to show that only the proton gradient was necessary for ATP synthesis?
A. complex I
B. ribonuclease
C. bacteriorhodopsin
D. actin

C. beta

Which subunit of ATP synthase is the site of phosphorylation of ADP?
A. alpha
B. subunit a
C. beta
D. subunit c

D. mitochondrial matrix

In animal cells, ATP synthase releases ATP into which of the following compartments?
A. cytoplasm
B. periplasm
C. inner membrane space
D. mitochondrial matrix

C. inner mitochondrial membrane

In animal cells, where is the Fo portion of ATP synthase located?
A. cytoplasm
B. plasma membrane
C. inner mitochondrial membrane
D. mitochondrial matrix

D. oxidative phosphorylation

In animal cells, the majority of ATP synthesized from the complete oxidation of glucose comes from which pathway?
A. glycolysis
B. gluconeogenesis
C. citric acid cycle
D. oxidative phosphorylation

B. gamma

This subunit of ATP synthase interacts with the beta subunits and rotates to induce their different conformations.
A. alpha
B. gamma
C. subunit c
D. subunit a

A. subunit c

This ATP synthase subunit forms a ring within the membrane and rotates as they carry protons.
A. subunit c
B. subunit a
C. gamma
D. beta

B. subunit a

Which ATP synthase subunit cintains two half channels for protons?
A. subunit c
B. subunit a
C. gamma
D. alpha

False

True or False: An ATP synthase with a ring comprised of more subunit c molecules is more efficient than one with a ring comprised of fewer subunit c molecules.

C. three

Vertebrate muscle ATP synthase has 8 subunit c molecules within its ring, how many ATP are produced per 360 degree rotation of the gamma subunit?
A. one
B. two
C. three
D. 2.667

True

True or False: The ADP-ATP translocase moves ADP into the mitochondrial matrix.

True

True or False: The ADP-ATP translocase is an example of passive diffusion

D. ADP

Acceptor control of oxidative phosphorylation means that the rate of electron transfer depends on what molecule?
A. NADH
B. ATP
C. oxygen
D. ADP

True

True or False: NADH formed during glycolysis in muscle cells enters the ETC via the glycerol shuttle.

A. Electron transfer from these molecules involves different complexes that do not contribute equally to the proton gradient

NADH and FADH2 do not yield equivalent amounts of ATP. Which of the following best describes why?
A. Electron transfer from these molecules involves different complexes that do not contribute equally to the proton gradient.
B. They have different redox potentials
C. NADH must always involve transport into the mitochondrial matrix.
D. all of the above

B. It transports NADH from glycolysis into the mitochondrial matrix of liver cells.

Which of the following best described the role of the malate-aspartate shuttle?
A. It transports NADH from the CAC into the inner membrane space or heart cells.
B. It transports NADH from glycolysis into the mitochondrial matrix of liver cells.
C. It transports NADH from the CAC into the mitochondrial matrix of muscle cells.
D. It transports FADH2 from glycolysis into the mitochondrial matrix of heart cells.

False

True or False: The malate-aspartate shuttle is a proton pump.

False

True or False: Protons travel from the matrix side of the inner mitochondrial membrane through ATP synthase to the IMS to drive ATP synthesis.

True

True or False: Protons travel down their concentration gradient through ATP synthase