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Population
any group of individuals of the same species living in the same geographical area at the same time
Gene
the basic unit of heredity; a specific sequence of DNA that encodes a protein, tRNA, rRNA molecule, or regulates the transcription of such a sequence; governs the expression of a particular trait and can be passed to an offspring
Allele
different form of the same gene occurring on homologous chromosomes
gene pool
total of all the alleles for all the genes of all the individuals in a population
genotype frequency
proportion of members of a population with a particular genotype; usually expressed as a decimal
phenotype frequency
proportion of members of a population with a particular phenotype; usually expressed as a decimal
allele frequency
rate of occurrence of a particular allele in a population, with respect to a particular gene; usually expressed as a decimal
Hardy-Weinberg principle
principle that states that allele and genotype frequencies remain constant from one generation to the next, as long as five conditions are met: (1) the population is large enough that chance events will not alter allele frequencies, (2) mates are chosen on a random basis, (3) there are no net mutations, (4) there is no migration, and (5) there is no natural selection against any of the phenotype
Hardy-Weinberg equation
mathematical description of the Hardy-Weinberg principle; used to predict allele and genotype frequencies in a population; usually stated
genetic equilibrium
condition of a gene pool in which allele frequencies remain constant over time; a population at genetic equilibrium is not changing or evolving; also known as Hardy-Weinberg equilibrium
Microevolution
gradual change in allele frequencies in a population over time
genetic diversity
degree of genetic variation within a species or population
Mutation
a permanent change in a cell’s DNA; includes changes in nucleotide sequence, alteration of gene position, gene loss, or duplication and insertion of foreign sequences; an inheritable mutation has the potential to affect an entire gene pool
gene flow
net movement of alleles from one population to another due to the migration of individuals and subsequent interbreeding
non-random mating
mating among individuals on the basis of mate selection for a particular phenotype or due to inbreeding, rather than mating on a random basis
genetic drift
change in allele frequencies due to chance events in a small breeding population; see also founder effect and bottleneck effect
founder effect
gene pool change that occurs when a few individuals start a new, isolated population; for example, on islands
bottleneck effect
gene pool change that results from a rapid decrease in population size
natural selection
process whereby the characteristics of a population of organisms change over time because individuals with certain heritable traits survive specific local environmental conditions and, through reproduction, pass on their traits to their offspring
heterozygote advantage
a survival benefit for those individuals who inherit two different alleles for the same trait (Aa), compared to those who are homozygous dominant or homozygous recessive; for example, the allele for cystic fibrosis may help carriers better resist diarrheal diseases such as cholera