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metabolic pathways
begin with a specific molecule and end with a product
- emergent property of life, regulated to maintain homeostasis
- it’s a series of chemical reaction, each involves energy transformation (each step is catalyzed by a specific enzyme
anabolic pathways
synthetic, making bonds requires energy
simple molecules which become complex molecules
- ex: synthesis of protein from amino acids
catabolic pathways
breaks bonds, release energy
complex molecules which become simple molecules
- ex: cellular respiration
energy
capacity to cause change/ do work
- movement of matter
two types: kinetic energy and potential energy
kinetic energy
the energy of motion
potential energy
stored energy, has not been used yet
thermodynamics
study of energy transformations
two laws:
energy cannot be created nor destroyed, only converted from one form to another - principle of conservation of energy
- ex: food which is chemical energy + heat
every energy transfer or transformation increases entropy in the universe
- entropy is the measure of disorder, randomness not usable -- disperse into environment
- ex: heat released during respiration
light energy
comes from the sun enters on ecosystem and heat energy exists
- energy conversion is never 100% efficient
- the total energy in the universe is constant
- total energy available to do work decreases
Gibbs free energy
the energy available to do work
- cannot be measured but we can see how free energy changes during a reaction
- change in energy = delta G
- if delta G is less than 0 than energy is released from reaction
- if delta G is greater than 0 than energy is added to cause a reaction, non spontaneous
- if delta G is equal to 0 than chemical processes at equalibrium
exergonic
- delta G energy released spontaneously
endergonic
+ delta G energy stored requires energy
cells use ATP to carry energy, its structure is
ribose (5-C sugar) , adenine (Nitrogen base), and 3 phosphate group
- coupled reactions pair endergonic reaction (requires energy) with exergonic reaction (provides energy)
ATP drives endergonic reactions by phosphorylation, phosphate group transferred to molecule, molecule now now shape
- reactant now = phosphorylated intermediate
enzymes speed up reactions by lowering energy barriers
activation energy
the initial energy needed to start a reaction
active site
cleft or groove for substrate binding
substrate
reactant that an enzyme acts upon
- change of shape , facilitates breaking of bonds
induced fit
enzyme changes shape after binding substrate for better fit, facilitates breaking/ forming bonds