fluoroquinolone

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Description and Tags

Aerospace Engineering

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4 Terms

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examples
ciprofloxacin, levofloxacin
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MOA
Inhibits DNA gyrase, Type II topoisomerase

Inhibits DNA replication and packaging of DNA within bacterial cell
3
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Uses
Gram -ve bacteria → chlamydia, mycobacteria

UTIs, RTOS, STIs, systemic
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Side effects
GI tract C.diff risk

Tendon damage

Photosensitivity

Interactions with CYP450 enzymes

Problems with resistance