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Nervous System
master controlling and communicating system of the body
perception, thought, memory, emotions, actions
maintenance of homeostasis
info to maintain normal temp
Sensory input
monitor stimuli inside and outside the body
Integration
interpretation of sensory input
Motor output
respond to stimuli by activation effector organs
Neurons
excitable cells that transmit electrical signals
principal cell type
Supporting cells
cells that surround and wrap neurons
Neuroglia/Glial cells
provide a supportive scaffolding for neurons
segregate and insulate neurons
guide young neurons to the proper connections
promote health and growth of neurons
Astrocytes
the most abundant CNS neuroglia
Microglial cells
defensive cells in the CNS
immune (phagocytes)
Ependymal cells
line cerebrospinal fluid-filled CNS cavities
circulate fluid in spinal cord
Oligodendrocytes
have processes that form myelin sheaths around CNS nerve fibers
Satellite cells & Schwann cells
form myelin sheaths that surround neurons in the PNS
Neurons (nerve cells)
components: body, axon, and dendrites
long-lived, amitotic, and have a high metabolic rate
plasma membrane functions:
electrical signaling
cell-to-cell signaling during development
Cell Body (Soma)
contains the nucleus, nucleolus, and other organelles
is the major biosynthetic center
Dendrites
short, tapering, and diffusely branched processes
receptive/input regions of the neuron
Axon functions
generate and transmit action potentials
secrete neurotransmitters from the axonal terminals
molecular transport
everything made in nucleus
Axon structure:
nerve fibers
usually only one axon per neuron, unbranched or with collaterals
axonal terminal
Nerve fibers
long axons
Axonal terminal
branched terminus of an axon
Anterograde transport
molecular transport from the soma to terminals
Retrograde transport
molecular transport from the terminals to soma
motor proteins
neurotransmitter components