Sessions 7 and 8 - Bacillus Gram-positive bacterial infections (1)

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26 Terms

1

Bacillus

A genus of large, aerobic, endospore-forming, motile Gram-positive rods.

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2

Bacillus anthracis

The causative agent of anthrax, characterized as encapsulated, large, box-car shaped, and nonmotile.

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3

Corynebacterium diphtheriae

A non-spore forming, facultatively anaerobic Gram-positive rod known to cause diphtheria.

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4

Listeria monocytogenes

A facultatively anaerobic, motile, Gram-positive bacillus that can cause listeriosis, particularly in immunocompromised individuals.

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5

Clostridium

A genus of Gram-positive, spore-forming rods that are obligately anaerobic and known for causing various types of infections.

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6

Exotoxins

Toxins secreted by bacteria that can cause damage to the host by disrupting normal cellular processes.

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7

Virulence factor

A trait of a microbe that contributes to its ability to cause disease.

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8

Endospore

A resistant dormant structure formed by some bacteria, which can survive extreme conditions.

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9

Transmission

The process by which an infectious agent is spread from one host or medium to another.

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10

Anthrax

A serious infectious disease caused by Bacillus anthracis, often affecting livestock and can be transmitted to humans.

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11

Tetanus

A serious bacterial infection caused by Clostridium tetani, characterized by painful muscle spasms.

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12

Pseudomembranous colitis

A colitis associated with antibiotic use, primarily caused by Clostridium difficile, marked by the presence of a pseudomembrane in the colon.

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13

Gastroenteritis

Inflammation of the gastrointestinal tract, often due to infection, leading to symptoms like diarrhea and vomiting.

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14

Lethal factor (LF)

A component of anthrax toxin that stimulates macrophages to release tumor necrosis factor (TNF)-α, inhibiting host's innate immunity.

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15

Protective antigen (PA)

A component of anthrax toxin that binds to receptors on host cells and facilitates the entry of other toxin components.

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16

Edema factor (EF)

A component of anthrax toxin that increases intracellular cAMP, leading to edema.

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17

Clostridial myonecrosis

A severe tissue infection caused by Clostridium species, often resulting in rapid muscle destruction and high mortality.

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18

Botulism

A condition caused by botulinum toxin, leading to muscle paralysis and potentially respiratory failure.

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19

Diphtheria toxin

The toxin produced by Corynebacterium diphtheriae, responsible for the symptoms of diphtheria by inhibiting protein synthesis.

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20

Listeriosis

An infection caused by Listeria monocytogenes, typically affecting pregnant women, newborns, and individuals with weakened immune systems.

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21

Food poisoning

Illness caused by consumption of contaminated food, leading to symptoms like abdominal pain and diarrhea.

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22

Incubation period

The time period between exposure to an infectious agent and the onset of symptoms.

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23

Facultative anaerobe

A microorganism that can grow in both the presence and absence of oxygen.

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24

Catalase positive

A property of certain bacteria that produce the enzyme catalase, allowing them to break down hydrogen peroxide.

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25

Pseudomembrane

A membrane-like structure formed in diphtheria due to necrotic tissue death, characterized by a grayish appearance.

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26

Hemolysis

The breakdown of red blood cells, often assessed in microbiological cultures.

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