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What is Calcitonin?
secreted by thyroid gland moves calcium from blood into bone
inhibits bone resorption by decreasing osteoclastic activity
if hypercalemia —> calcatonin increased
What is Parathyroid Hormone?
secreted by parathyroid gland moves calcium from bone to blood
stimulates bone resorption by increasing osteoclastic activity
if hypocalemia —> PTH increased
What is osteoporosis?
general term meaning pathologically “porous bone.”
resorption(PTH) will increase due to increased osteoclastic activity - break down bone
this causes bone density to decrease, and bone becomes more porous
What is Osteopenia?
the condition of having somewhat less than normal bone density
What are the treatments of osteoporosis?
once osteopenia is identified by a bone density study, medications may be prescribed to decrease osteoclastic activity,
such as nasal calcitonin and biphosphonates(Fosamax)
What are the Electrical issues regarding calcium?
hypo or hypercalcemia can affect Na+ movement in and out of cells, thus affecting RMP
What are the Clotting issues regarding calcium?
low calcium = low clotting ability(hypocalcemia)
a patient might have easy bleeding, manifested as petechiae and purpura.
What are the Urological issues regarding calcium?
hypercalcemia can cause kidney stones
What causes Hypocalcemia?
Hypoparathyroidism
Calcitonin Hypersecretion
What causes Hypercalcemia?
Hyperparathyroidism
Calcitonin Hyposecretion