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Vocabulary flashcards covering high-risk newborns, late-preterm infants, Respiratory Distress Syndrome, Neonatal Sepsis, Necrotizing Enterocolitis, Neonatal Seizures, and Neonatal Abstinence Syndrome based on lecture notes.
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High-Risk Newborn
A newborn with an increased chance of morbidity or mortality occurring at any gestational age, influenced by prematurity, congenital anomalies, respiratory issues, infection, and metabolic instability.
Gestational Age (Neonatal Outcome Predictor) NCLEX Pearl
The single best predictor of neonatal outcomes, as opposed to birth weight.
Late-Preterm Infants
Infants who often look term, but have immature organs—especially lungs and brain—and struggle with respiratory distress, temperature instability, hypoglycemia, feeding coordination, jaundice, bilirubin clearance, and delayed discharge.
Late-Preterm Infants NCLEX Pearl
At high-risk for hypoglycemia caused by immature hepatic glucose regulation.
Transporting High-Risk Newborns
Stabilize first, regulate temperature, maintain oxygenation, monitor vitals, ensure hydration, use trained transport teams
Primary Transport Threats for High-Risk Newborns
Hypothermia and hypoxia.
Key Assessments in High-Risk Infants
Respiratory status, cardiovascular stability, GI tolerance, GU output, neurologic tone/behavior, temperature, skin integrity
Neonatal Jitteriness vs. Seizures NCLEX Pearl
An assessment distinction where jitteriness that does not stop with gentle flexion suggests seizures, not hypoglycemia.
Feeding Intolerance
Normally the first sign of Necrotizing Enterocolitis (NEC) or Sepsis in a newborn.
Poor Feeding Behaviors S/S
Apnea, bradycardia, and cyanosis accompanying poor feeding in high-risk infants.
Necrotizing Enterocolitis (NEC) Red Flags
Abdominal distention, absent bowel sounds, emesis, and large gastric residuals; requires stopping feeding and notifying the provider immediately.
NEC NCLEX Pearl
High gastric residual + abdominal distention + absent bowel sounds = hold feeding for possible NEC
Respiratory Distress Syndrome (RDS)
A condition in preterm infants caused by a lack of mature alveoli and surfactant, managed with surfactant replacement and ventilatory support.
Surfactant replacement improves lung expansion and oxygenation; overuse of oxygen increases the risk of retinopathy, prematurity, or ROP
S/S: retractions, nasal flaring, grunting
Retinopathy of Prematurity (ROP) Risk Factor
The overuse of oxygen during hypoxemia management in preterm infants.
Hypoxemia management
surfactant therapy, ventilatory support, judicious oxygen use
Grunting in Infants NCLEX Pearl
The infant creating their own positive expiratory pressure (PEP), serving as an early sign of respiratory failure.
Early-Onset Neonatal Sepsis
Sepsis occurring at <3 days of age, resulting from maternal transmission.
Late-Onset Neonatal Sepsis
Sepsis occurring at 1–3 weeks of age, often hospital-acquired and presenting with temperature instability, poor feeding, lethargy, and respiratory distress.
Respiratory distress diagnostics: blood, urine, CSF cultures
Neonatal Sepsis Temperature Sign NCLEX Pearl
Hypothermia (low temperature), rather than fever, which is one of the most common early signs of neonatal sepsis.
early antibiotics save lives
Necrotizing Enterocolitis (NEC)
One of the most common GI emergencies in preterm infants; risk factors include prematurity, intestinal ischemia, and pathogenic bacteria.
NEC Risk factors: prematurity, intestinal ischemia, pathogenic bacteria
Breast Milk Protection Against NEC
Protective effect provided by breast milk against NEC due to its content of IgA and macrophages.
Necrotizing Enterocolitis (NEC) Management
Medical interventions including keeping the infant NPO, NG decompression, IV antibiotics, TPN, and surgery if bowel perforation occurs.
Neonatal Seizures
Often subtle seizure manifestations in newborns including lip smacking, bicycling movements, and eye deviations.
require immediate evaluation
Causes: metabolic issues, infection, trauma, drug withdrawal treatment
Drug withdrawal treatment: treat underlying cause, phenobarbital, phenytoin, and benzodiazepines
Neonatal Abstinence Syndrome (NAS)
Withdrawal in newborns that typically begins within 12–24 hours after birth depending on the substance, presenting with irritability, tremors, a shrill cry, poor feeding, and diarrhea.
Seizure management: swaddling, low-stimulation environment, morphine or methadone, supportive feeding
Classic NAS Triad NCLEX Pearl
The combination of high-pitched cry, tremors, and diarrhea indicating Neonatal Abstinence Syndrome.
Discharge Planning for Medically Fragile Infants
An early-initiated process that includes car seat testing, feeding stability, temperature stability, parent education, follow-up appointments, and clear care instructions.