Ch. 9 The High-Risk Newborn and Family

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Vocabulary flashcards covering high-risk newborns, late-preterm infants, Respiratory Distress Syndrome, Neonatal Sepsis, Necrotizing Enterocolitis, Neonatal Seizures, and Neonatal Abstinence Syndrome based on lecture notes.

Last updated 2:38 AM on 9/17/26
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28 Terms

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High-Risk Newborn

A newborn with an increased chance of morbidity or mortality occurring at any gestational age, influenced by prematurity, congenital anomalies, respiratory issues, infection, and metabolic instability.

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Gestational Age (Neonatal Outcome Predictor) NCLEX Pearl

The single best predictor of neonatal outcomes, as opposed to birth weight.

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Late-Preterm Infants

Infants who often look term, but have immature organs—especially lungs and brain—and struggle with respiratory distress, temperature instability, hypoglycemia, feeding coordination, jaundice, bilirubin clearance, and delayed discharge.

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Late-Preterm Infants NCLEX Pearl

At high-risk for hypoglycemia caused by immature hepatic glucose regulation.

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Transporting High-Risk Newborns

Stabilize first, regulate temperature, maintain oxygenation, monitor vitals, ensure hydration, use trained transport teams


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Primary Transport Threats for High-Risk Newborns

Hypothermia and hypoxia.

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Key Assessments in High-Risk Infants

Respiratory status, cardiovascular stability, GI tolerance, GU output, neurologic tone/behavior, temperature, skin integrity


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Neonatal Jitteriness vs. Seizures NCLEX Pearl

An assessment distinction where jitteriness that does not stop with gentle flexion suggests seizures, not hypoglycemia.

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Feeding Intolerance

Normally the first sign of Necrotizing Enterocolitis (NEC) or Sepsis in a newborn.

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Poor Feeding Behaviors S/S

Apnea, bradycardia, and cyanosis accompanying poor feeding in high-risk infants.

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Necrotizing Enterocolitis (NEC) Red Flags

Abdominal distention, absent bowel sounds, emesis, and large gastric residuals; requires stopping feeding and notifying the provider immediately.

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NEC NCLEX Pearl

High gastric residual + abdominal distention + absent bowel sounds = hold feeding for possible NEC 

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Respiratory Distress Syndrome (RDS)

A condition in preterm infants caused by a lack of mature alveoli and surfactant, managed with surfactant replacement and ventilatory support.

  • Surfactant replacement improves lung expansion and oxygenation; overuse of oxygen increases the risk of retinopathy, prematurity, or ROP 

  • S/S: retractions, nasal flaring, grunting


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Retinopathy of Prematurity (ROP) Risk Factor

The overuse of oxygen during hypoxemia management in preterm infants.

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Hypoxemia management

surfactant therapy, ventilatory support, judicious oxygen use

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Grunting in Infants NCLEX Pearl

The infant creating their own positive expiratory pressure (PEP), serving as an early sign of respiratory failure.

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Early-Onset Neonatal Sepsis

Sepsis occurring at <3 days< 3\text{ days} of age, resulting from maternal transmission.

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Late-Onset Neonatal Sepsis

Sepsis occurring at 13 weeks1\text{--}3\text{ weeks} of age, often hospital-acquired and presenting with temperature instability, poor feeding, lethargy, and respiratory distress.

  • Respiratory distress diagnostics: blood, urine, CSF cultures 


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Neonatal Sepsis Temperature Sign NCLEX Pearl

Hypothermia (low temperature), rather than fever, which is one of the most common early signs of neonatal sepsis.

  • early antibiotics save lives 


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Necrotizing Enterocolitis (NEC)

One of the most common GI emergencies in preterm infants; risk factors include prematurity, intestinal ischemia, and pathogenic bacteria.

  • NEC Risk factors: prematurity, intestinal ischemia, pathogenic bacteria


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Breast Milk Protection Against NEC

Protective effect provided by breast milk against NEC due to its content of IgA and macrophages.

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Necrotizing Enterocolitis (NEC) Management

Medical interventions including keeping the infant NPO, NG decompression, IV antibiotics, TPN, and surgery if bowel perforation occurs.

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Neonatal Seizures

Often subtle seizure manifestations in newborns including lip smacking, bicycling movements, and eye deviations.

  •  require immediate evaluation

  • Causes: metabolic issues, infection, trauma, drug withdrawal treatment

  • Drug withdrawal treatment: treat underlying cause, phenobarbital, phenytoin, and benzodiazepines 


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Neonatal Abstinence Syndrome (NAS)

Withdrawal in newborns that typically begins within 1224 hours12\text{--}24\text{ hours} after birth depending on the substance, presenting with irritability, tremors, a shrill cry, poor feeding, and diarrhea.

  • Seizure management: swaddling, low-stimulation environment, morphine or methadone, supportive feeding 


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Classic NAS Triad NCLEX Pearl

The combination of high-pitched cry, tremors, and diarrhea indicating Neonatal Abstinence Syndrome.

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Discharge Planning for Medically Fragile Infants

An early-initiated process that includes car seat testing, feeding stability, temperature stability, parent education, follow-up appointments, and clear care instructions.