Overview of the Urea Cycle

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8 Terms

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N-acetylglutamate (NAG)

Activates carbamoyl phosphate synthetase-1 in urea cycle.

2
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Carbamoyl phosphate synthetase-1 (CPS-1)

Enzyme that catalyzes carbamoyl phosphate formation.

3
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Ornithine

Amino acid that combines with carbamoyl phosphate.

4
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Citrulline

Product of ornithine and carbamoyl phosphate reaction.

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Argininosuccinate synthetase

Enzyme that converts citrulline and aspartate to argininosuccinate.

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Arginase

Enzyme that hydrolyzes arginine to urea and ornithine.

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Fumarate

Intermediate produced during argininosuccinate breakdown.

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Urea

Final product of the urea cycle, excreted in urine.