Intro Antibiotics & Drug Resistance

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8 Terms

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Narrow Spectrum

act only on a single or a limited group of microorganisms

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Extended Spectrum

effective against gram-positive organisms and also against a significant number of gram-negative bacteria.

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Broad Spectrum

affect a wide variety of microbial species

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B-Lactams

cell wall synthesis inhibitor

penicillins, carbapenems, monobactams

resistance due to: synthesis of B-lactamase enzyme

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Vancomycin

inhibit cell wall synthesis

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Tetracycline, Macrolides, Aminoglycosides

protein synthesis inhibitors

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Quinolones, Fluoroquinolones, Metronidazole

nucleic acid synthesis inhibitors

inhibit DNA replication - DNA gyrase inhibitors

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sulfonamides, trimethoprim

metabolism inhibitors