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Flashcards covering common medications (brand/generic/class), federal pharmacy requirements and laws, patient safety protocols, and prescription SIG codes based on lecture transcript notes.
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Lisinopril
An ACE inhibitor used to treat hypertension by relaxing blood vessels.
Antibiotics
Treats bacterial infections
Bactericidal Antibiotics
Kills bacteria directly
Bacteriostatic Antibotics
Blocks/Inhubits bacterial growth
Categories of Antibiotics
Penicillins & Cephalsporins
Penicillin’s & Cephalosporins
Blocks/Inhibits bacterial cell wall synthesis
Are beta-lactam antibiotics
Includes Amoxicillin (penicillin) and Cefalexin (cephalosporin)
Tetracyclines
Inhibits/Blocks protien synthesis by binding to bacterial ribosomes
Tetracyclines prevent…
Bacterial growth.
Fluoroquinolones
Blocks/Inhibits bacterial DNA replication
Fluoroquinolones Target what?
DNA gyrase & topisomerase IV
Macrolides
Block/Inhibits bacterial protein synthesis
Macrolides Bind to…
Ribosome subunits
Example of Macrolides
Azithromycin
Lipitor
Brand name for Atorvastatin, a statin medication used to lower cholesterol.
Furosemide
A loop diuretic used to remove excess fluid and treat hypertension; also known by the brand name Lasix.
Metformin
A first-line medication for type 2 diabetes that improves insulin sensitivity and manages blood glucose levels.
Omeprazole
A proton pump inhibitor (PPI) used to reduce stomach acid production for conditions like GERD and ulcers.
Simvastatin
A statin used to lower LDL cholesterol and reduce the risk of cardiovascular events.
Opioids
A class of medications, such as hydrocodone, that frequently cause constipation by slowing gastrointestinal motility.
Warfarin
An anticoagulant that prevents blood clots by inhibiting vitamin K-dependent clotting factors; it is contraindicated during pregnancy.
Albuterol
A short-acting beta-2 agonist (SABA) used as a bronchodilator for asthma and COPD.
Fluconazole
An antifungal medication used to treat infections such as candidiasis.
Levothyroxine
A synthetic form of thyroid hormone used to treat hypothyroidism by replacing deficient hormones.
Acetaminophen
A medication used for pain and fever with a maximum adult daily dose of 4grams to avoid liver toxicity.
Sertraline
An SSRI (selective serotonin reuptake inhibitor) commonly used to treat depression and anxiety.
Naloxone
An opioid antagonist used to reverse the effects of an opioid overdose; also known as Narcan.
Advair Diskus
A combination medication containing fluticasone (corticosteroid) and salmeterol (long-acting beta-agonist) for asthma and COPD.
Atorvastatin
A statin medication that requires patients to avoid grapefruit because it interferes with metabolism and increases side effect risks.
Poison Prevention Packaging Act
Federal law requiring child-resistant packaging for most prescriptions to prevent accidental ingestion by children.
DEA Form 222
The form used by pharmacies to order, transfer, or return Schedule II controlled substances.
Schedule II Controlled Substances
Drugs with a high potential for abuse but accepted medical uses, such as oxycodone and fentanyl.
Schedule III-IV Refill Limit
Prescriptions that may have up to 5 refills within 6 months of the original prescription date.
Prescriber’s DEA Number
A required component for a controlled substance prescription to be considered valid.
HIPAA
The Health Insurance Portability and Accountability Act, which ensures the confidentiality and protection of patient health information.
Combat Methamphetamine Epidemic Act (CMEA)
A 2005 law regulating the OTC sale of pseudoephedrine, setting purchase limits of 3.6grams per day and 9grams per 30-day period.
DEA Form 106
The form used to document and report significant theft or loss of controlled substances.
OBRA-90
The Omnibus Budget Reconciliation Act of 1990, which mandates that pharmacists offer counseling to Medicaid patients.
Schedule I Controlled Substances
Drugs with no accepted medical use in the U.S. and a high potential for abuse, such as heroin and LSD.
Durham-Humphrey Amendment
Federal law that established the legal distinction between prescription and over-the-counter (OTC) drugs.
LASA
Stands for Look-Alike, Sound-Alike; refers to medications with similar spelling or pronunciation that pose a risk for errors.
Medication Barcoding System
A technology used to ensure the correct medication is dispensed by matching the barcode on the medication to the prescription.
ISMP
The Institute for Safe Medication Practices, which provides resources and the 'Do Not Use' list to prevent medication errors.
High-Alert Medications
Medications, such as insulin and anticoagulants, that pose a higher risk of causing significant harm if used inappropriately.
Tall Man Lettering
A method of highlighting differences in look-alike, sound-alike drug names to reduce errors, such as 'predniSONE' vs. 'predniSOLONE'.
Root Cause Analysis (RCA)
A systematic quality assurance process used to identify underlying causes of a medication error to prevent recurrence.
Class I Recall
The most severe drug recall, involving medications that pose a high risk of serious health consequences or death.
Stock Rotation
The practice of placing medications with the earliest expiration dates at the front to ensure older stock is used first.
MedWatch
A program that allows healthcare professionals and patients to report adverse drug reactions and product defects to the FDA.
BID
SIG code meaning 'twice a day' (bis in die).
QID
SIG code meaning 'four times a day' (quater in die).
TID
SIG code meaning 'three times a day' (ter in die).
AC
SIG code meaning 'before meals' (ante cibum).
PC
SIG code meaning 'after meals' (post cibum).
HS
SIG code meaning 'at bedtime' (hora somni).
PRN
SIG code meaning 'as needed' (pro re nata).
PO
SIG code meaning 'by mouth' (per os).
Gtt
SIG code meaning 'drop' (guttae).
DAW
Stands for 'Dispense As Written'; indicates the pharmacist must dispense the brand-name medication and not a generic equivalent.
ODT
Stands for 'Orally Dissolved Tablet'; a tablet that dissolves on the tongue for rapid absorption.
QS
SIG code meaning 'quantity sufficient'.
Subscription
The part of the prescription that contains instructions for the pharmacist, such as how to compound or dispense the medication.
Inscription
The part of the prescription that lists the name, strength, and dosage form of the medication.
Analgesics
Relives pain and discomfort without loss of conciousness.
Opiods - Analgesics
Acts on the centeral nervous system to relive pain.
Non-Opiods - Analgesics
Reduces inflammation at the site of pain.
Opiods bind to what? - Analgesics
Binds to opiod receptors like the brain, spinal cord, and other organs.
NSAID’s
Non-Steril Antinflamitory Drug that inhibit enzyme COX (cycloocygenase) that mediate pain.
Antihypertensives manage what?
Manages blood pressure
Antihypertensives include what class?
ACE Inhibitors - Angiostensin-Converting Enzyme Inhibtiors
Antihypertensives are a potent what?
Vasoconstrictor
Beta-Blockers do what?
Reduce Blood pressure, Blocks Effects of hormones, Slows heart rate, Reduces force of heart musclecontraction, and treats Nervous system conditions of Anxiety.
Diuretics help eliminate what?
Excess salt and water through urination.
Diuretics reduce what?
Blood pressure and Swelling.
Diuretics inhibit what?
Reabsorption of Sodium and Chloride.
Diuretics act on what organ?
The Kidney’s
Loop Diuretics
Acts on Loop of the Henle in the Kidneys.
Thiazide Diuretics
Acts on distal convoluted tuble, treating hypertension and chloride.
Anti-Diabetics treat what?
Diabetes mellitus by lowering glucose levels in the blood.
Insulins reduce or increase glucose in cells?
Reduce.
Sulfonylureas stimulate what? - Anti-Diabetics
The Panceas - to produce more more insulin
Biguanides (like Metformin)
Reduces levels of glucose produced by the liver.
Oral Hypoglycemic
Lowers high blood sugar levels.
Stains Class
Class of Lipid-Lowering Meds
Stains have what enzyme?
Enzyme HMG-CoA - Helps the liver lower cholesterol
Stains lower what?
Lowers levels of LDL cholesterol
Receptor Interation
Binds to receptors on surface of cells, Triggers/Inhibits biological responses, and Beta-Blockers inhibits beta-adrenergiv receptors to reduce heart rate.
Enzyme Inhibition
When some drugs block enzymes to prevent production of compounds, and NSAID’s inhibiting CoX enzymes to reduce inflamation.
Ion Channel Modulation
Calcium Channel blockers that regulate ion flow in-and-out of cells, and controls Vascular resistance and heart rate.
Selective Toxicity
Antibiotics that target Bacterial cells without harming human cells, and Penicillins disrupt bacterial bacterial cell walls.
Pain Relievers
Acetaminophen & Ibuprofen
Antibiotic Meds
Amoxicillin & Azithromycin
Blood Pressure Meds
Lisinopril & Amlodipine
Cholesterol Meds
Atorvastin
Beta-Blockers may cause…
Fatiuge
Beta-Blockers should be avoided in what patients?
Asthmatic Patients - Because of risking Bronchoconstriction
NSAID’s increase risk of…
Gastrointestional bleeding, especially in people with history of ulcers.
Ibuprofen brand names
Advil & Motrin
Generic Drugs are…
Less expensive
Generic drugs may differ in what ingredients?
Fillers, Dyes, or inactive ingredients.