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what are the 3 main stages of the cell cycle
interphase (90%)
mitosis
cytokinesis
what are specialised cells
cells that have differentiated to perform a specific function
what is an erythrocyte
a red blood cell
contains haemoglobin which binds to oxygen to transport it from the lungs to body tissues
how are erythrocytes specialised to their role (3)
biconcave so increased surface area
no nucleus so more space for haemoglobin
flexible to allow passage through narrow capillaries
what is a neutrophil
a type of white blood cell involved in phagocytosis with a cytoplasm filled with lysosomes to break down phagocytosed material
where are erythrocytes replaced
are constantly being produced by bone marrow as they only have a lifespan of 120 days
where are neutrophils replaced
bone marrow
what is a cell
a specialised unit that has differentiated to carry out a specific function
what is a tissue
a collection of differentiated cells with a specialised function
what is an organ
a collection of tissues adapted to perform a particular function
what is an organ system
a number of organs working together to carry out a major function
what is an organism
a living entity that can function independently
what is the epidermis and what is it made of
the thin outer layer of the skin that consists of squamous cells basal cells and melanocytes
what are squamous cells
cells that make up the outermost layer which are continuously shed
what are basal cells
cells found at the base of the epidermis
what are melanocytes
cells found at the base of the epidermis that make melanin and gives skin its colour
what re 8 things the dermis consists of
blood vessels
lymph vessels
hair follicles
sweat glands
collagen bundles
fibroblasts
nerves
sebaceous glands
what is the role of collagen in the dermis
it holds the dermis together and gives skin flexibility and strength
where do specialised cells originate from
undifferentiated stem cells
what is a stem cell
a cell that can divide an unlimited number of times and develop into any cell
what is division in stem cells
stem cells divide by mitosis to produce new cells
what is differentiation
the process by which a stem cell becomes a specialised cell
what is potency
a level of how many types of cells stem cells can differentiate into
what are the 3 potencies
totipotent
pluripotent
multipotent
what is totipotent
can become any body cell including cells in placenta and umbilical cord (usually in zygotes)
what is pluripotent
can form any type of body cells but no placenta or umbilical cord (usually in embryos)
what is multipotent
can form more than one type of cell but not all types of body cells (adult stem cells, usually in bone marrow)
what is a blastocyst
a ball of cells that form during early pregnancy
why is differentiation important
groups of cells with different functions working together as one unit can make use of resources more efficiently that single cells operating on their own
what are embryonic stem cells
totipotent stem cells found in embryos
once embryos form a blastocyst stem cells become pluripotent
where are plant stem cells found
in meristems which is wherever growth is occurring
where is meristematic tissue found
shoots and roots
vascular cambium (between xylem and phloem tissues)
what is the potency of meristems
pluripotent but meristematic tissue in the vascular cambium typically differentiate into cells present in xylem and phloem
what are 7 diseases that have the potential to be treated using stem cells
heart disease
type 1 diabetes
parkinson’s disease
alzheimer’s disease
macular degeneration
birth defects
spinal injury
how are stem cells used to treat heart disease
muscle tissue that was permanently damaged as a result of a heart attack can be replaced
how is type 1 diabetes treated using stem cells
the body’s own immune system destroys insulin producing cells in the pancreas
stem cells can be used to make insulin producing cells
how is parkinson’s disease treated using stem cells
dopamine-producing cells are replaced which delays the progress of the disease and symptoms
how is alzheimer’s treated using stem cells
brain cells that are destroyed as a result of the build up of abnormal proteins are replaced to alleviate symptoms
what are 2 current uses of stem cells
replacing cells damaged from burns by growing them on biodegradable mesh
drugs are tested on stem cells before humans and animals
what are the ethical issues around embryonic stem cells
removal of stem cells from embryos normally result in the destruction of the embryos which lead to moral and religious objections
what is the function of squamous epithelium
allows for rapid diffusion
what is the structure of squamous epithelium
made up of many flat squamous epithelial cells
one cell thick so very short diffusion distance
what is the function of ciliated epithelium
prevents unwanted particles reaching alveoli in the lungs
what is the structure of ciliated epithelium
made of ciliated epithelial cells with hair like cilia
cilia wafts mucus (that’s released from goblet cells) away from the lungs
what is the function of cartilage
prevents end of bones rubbing together
can be structural (e.g. forms skeleton of some fish)
what is the structure of cartilage
a connective tissue made of chondrocyte cells embedded in an extracellular matrix composed of fibres of elastin and collagen
what is the function of muscle
allows movement by contracting
what is the structure of muscle
skeletal muscle fibres are made of myofibrils which contain contractile proteins
what is the structure of the epidermis
single layer of closely packed cells covered by a waxy cuticle to reduce water loss
what is the function of xylem
transports water and minerals throughout the plant
what is the structure of xylem
vascular tissue made of elongated dead cells strengthened by lignin
what is the function of phloem
transports organic nutrients throughout the plant
what is the structure of phloem
vascular tissue composed of columns of sieve tubes cells separated by perforated sieve plates
what is the structure of neutrophils
multi lobed nucleus to make it easier to squeeze through gabs to infection sites
granular cytoplasm contained lysosomes to attack pathogens
what is the structure of sperm
has a flagellum for movement
contains many mitochondria for energy
acrosome contains digestive enzymes which aids fertilisation
what is the function of root hair cells
uptakes water and minerals from soil
what is the structure of root hair cells
long extension near growing tips of the roots to increase surface area
what is the function of guard cells
allows carbon dioxide to enter the plant for photosynthesis
opens and closes to control water and oxygen loss and uptake
what is the structure of palisade cells
rectangular cells that can tightly pack together
thin walls to increase rate of diffusion of carbon dioxide
large vacuole to maintain turgor pressure
what is the role of palisade cells
contains many chloroplasts for photosynthesis