Dental materials

risk factors for caries

Poor diet

Previous caries

polypharmacy

Xerostomia

primary prevention (caries) (examples)

Prevention of disease

• Oral hygiene instructions (OHI)

• diet modifications

• sealents

• minerilizing agents

secondary prevention (caries)

includes detection and treatment of early lesions

• radiographs and visual changes to detect caries

• slow or arrest early decay.

tertiary prevention (caries)

treating the decay to prevent further tissue damage

• Interim therapeutic restorations

• Direct restorations (amalgam,

  composite, glass ionomer)

patient - level intervention

re-establish mineral balance

• diet change

• OHI

Lesion - level intervention

non-restorative / non-surgical

minimally invasive vs invasive

what do calcium phosphate products do

Induces hydroxyapatite formation

Promotes remineralization and desensitizing

critical PH of Calcium phosphate products

5.5

calcium phosphate pastes goal

• Reinforces enamel and dentin minerals

• closes dental tubules

what calcium phosphate is closest to bone

hydroxyapatite

most stabel calcium phosphate product

hydroxyapatite

tricalcium phosphate (TCP)

• less stable than HAP and more soluble

• precipitation of an apatite layer upon incubation in aqueous ionic solutions

amorphous calcium phosphate (ACP)

• Produced by rapid precipitation of calcium and phosphate ions from aqueous solutions

• release a host of ions (can change the PH)

antimicrobial peptides

• preform biological functions

• immune defense (plants/invertabraes)

?????????

what do antimicrobial peptides do

• specific targets

• Small Molecular Antibiotics

  • Target Multiple Microbes

    Promote Resistance

    Affect the (Oral) Microbiome

what breaks down in saliva

antimicrobial peptides