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Cardiomyopathy
A collection of diverse conditions of the heart muscle
Many caused, symptoms and treatments that affect people of all ages and races
Can be developed bc of another disease, condition, factor or inherited
3 types
Dilated Cardiomyopathy
Hypertrophic Cardiomyopathy
Restrictive Cardiomyopathy
Dilated Cardiomyopathy
Ventricular chamber enlargement with impaired (weak) systolic contractile function (how well it squeezes and pumps)
Usually dilated in Left ventricle
Weak contraction of heart muscle
Decrease ejected fraction
Leads to systolic dysfunction (not working right)
Etiology (the cause) of DCM
Idiopathic- unknown cause (dr can’t identify why)
Familial (genetic)/primary- inherited (passed down in genes)
Inflammatory/secondary- affected/ another disease
Viral Myocarditis (infectious)- infects and inflames the muscle→ weakens
Connective tissue diseases (noninfectious)- autoimmune (attack it’s self) immune system causes inflammation in heart
Toxic- damage from harmful substances
Chronic excessive alcohol ingestion- weak heart over time
Chemotherapeutic agents- cancer drugs that damage heart cells
Metabolic- problems with body chemistry/ hormones affecting the heart
Hypothyroidism- low thyroid hormone slows body processes and weak heart function
Pathology (things you see in the heart) in DCM
Makes enlargement of all four cardiac chambers is typical of DCM- all 4 chambers become dilated bc blood backs up and the heart remodels over time
Sometimes the disease may be limited to left or right side of the heart- not all 4 chambers are affected
Left: most common→ affects pumping to the body
Right: less common→ affects lungs circulation
Pathophysiology of DCM