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Isotonic dehydration
dehydration that does not cause osmotic water shift from ICF
ascites, diuretic therapy, GI fluid losses, aspiration of pleural effusion, inadequate fluid and salt intake
etiology of isotonic dehydration
hypertonic dehydration
-water loss exceeds salt loss
-osmotic shift of water from cells in ECF
vomiting, sweat loss, osmotic diuresis, osmotic diarrhea, inadequate water intake
etiologies of hypertonic dehydration
hypotonic dehydration
-most salt lost than water
-osmotic shift of water from ECF into cells
-sweat loss, GI fluid loss, thiazide diuretics, water replacement without adequate sodium and potassium replacement
etiologies of hypotonic dehydration
5mL solutions every 2 minutes should be obtained orally with the goal aimed at 10mL/kg for each stool
appropriate rehydration method for mild dehydration
50-100mL/kg over 3-4 hours should be obtained orally. This should be started with 5mL every 5 minutes
appropriate rehydration method for moderate dehydration
An IV bolus of 30-60mL should be started on a continuous infusion depending on the patients' weight. (For example if the pt weighs less than 20 kg give 1000 mL/d plus 50 mL/kg/d for each kilogram between 10 and 20 kg)
appropriate rehydration method for severe dehydration
%dehydrationn x Wt (kg) x 10
how do you calculate a volume deficit
-inadequate water intake
-excess water loss
-excess sodium intake (rarely)
common causes of hypernatremia
-thirst
-change in mental status---> drowsiness, restlessness, confussion, and lethargy, to seizure and coma
clinical manifestations of hypernatremia
-primary water deficit: IV NS or hypotonic fluids
-tx underlying cause
management of hypernantremia
-loss of sodium containing fluids
-excess water gain
-inadequate sodium intake (rare)
common causes of hyponatremia
-HA, irritability, difficulty concentrating
-severe: confusion, vomiting, seizures, coma
clinical manifestations of hyponatremia
-in case of water excess: fluid restriction, diureticss, small amount of hypertonic saline in case of seizures
-abnormal fluid loss: fluid replacement using isotonic sodium containing solutions, encourage oral intake
management of hyponatremia
-nausea, slow/weak pulse, sudden collapse
-numbness (usually in hands, arms, legs or feet)
-muscle weakness
-diarrhea or abdominal cramping
symptoms of hyperkalemia
depressed ST segment
diphasic T wave
prominent U wave
EKG findings of hypokalemia
-peaked T wave----> worsens to wide PR interval, wide QRS---> loss of sinusoidal p wave
ekg findings of hyperkalemia
Anorexia
Nausea
Vomiting
Sluggish bowel
Cardiac arrhythmias
Postural hypotension
Muscle fatigue
Weakness
Leg cramps
Decreased DTRs
symptoms of hypokalemia
methanol
uremia
DKA
isoniazid
lactic acidosis
ethanol/ethyllene glycol
salicylates
list the causes of metabolic acidosis (MUDPILES)
SIADH (CNS infections, head trauma, certain drugs)
CHF, nephrotic syndrome, cirrhosis (hypervolemic)
Excess hypotonic fluid intake (psychogenic polydipsia)
causes of hyponatremia
hypokalemia
constipation, muscle cramps is sin of what elecrtolyte imbalance
pseudohyperkalemia
Caused by prolonged use of tourniquet when drawing blood +/- fist clenching, causes acidosis and subsequent K loss from those cells but not true hyperkalemia
hyperkalemia
what electrolyte imbalance can cause weakness, paresthesias
-3% body weight loss as a resutl of fluid loss
-slight thirst, decreased urine frequency
classify milld dehydration
-6% decrease in body weight
-irritable or lethargic, dry mucus membranes
classiffy moderate dehydration
>10% in inants >7% in older children loss of body weight from fluid loss
classify severe dehydration
hypotension
______ is a late sign of shock