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COVID 19
is a human respiratory illness transmitted person-to-
person primarily via respiratory droplets as well as
contact with contaminated surfaces caused by a novel
coronavirus, SARS-CoV-2
sars-cov-2 or coronavirus
What is the causative agent?
•Droplet (coughing, sneezing, talking, singing)
•Direct, indirect or close contact with infected people
through infected secretions such as saliva and
respiratory secretions or their respiratory droplets;
touching surfaces in the immediate environment or with
objects used on the infected person
•Airborne (can occur during medical procedures: ET
insertion, bronchoscopy, manual ventilation, suctioning,
administration of nebulized treatment, turning the
patient to the prone position, disconnecting the patient
from the ventilator, non-invasive positive-pressure
ventilation, tracheostomy, and cardiopulmonary
resuscitation.
What is the mode of transmission?
1. Age: Most reported cases are in adults of middle age or older
2. Sex/ Gender: females are more often affected, but disease is more severe in males
3. Various underlying medical conditions (CKD, COPD and so on) and certain disabilities
4. Immunocompromised
5. Those who reside in long-term care or skilled nursing facilities
What are the risk factors?
- Fever, cough, sore throat, congestion
- Fatigue, headache, myalgia
- Loss of taste/smell
- Shortness of breath
- GI symptoms (sometimes)
What are the common symptoms?
Respiratory: Pneumonia, ARDS, pulmonary embolism
Cardiac: Myocarditis, arrhythmias, heart failure, clots
Neurologic: Stroke, encephalopathy, loss of taste/smell
Renal: Acute kidney injury
Hematologic: Blood clots, DIC, thrombocytopenia
Long COVID: Fatigue, brain fog, dyspnea, palpitations
Other: Secondary infections, MIS
“Lungs, Heart, Brain, Kidneys, Blood → think multi-organ”
What are the complications?
Reverse-transcriptase polymerase chain reaction test (RT-PCR)
Antigen Rapid Tests
What is the definitive test and supporting tests?
- Corticosteroids (dexamethasone)
- Antivirals (remdesivir in hypoxic cases)
- Monoclonal antibodies (for outpatients at high risk)- Bamlanivimab
What are the medications?
- Infection control, isolation, PPE for healthcare workers
- Client and family education on hygiene, social distancing, symptom monitoring
What are examples of management?