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Flashcards reviewing the hormonal control of male reproduction, including GnRH, FSH, LH, testosterone, ABP, and inhibin.
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What is GnRH?
A hormone produced by the hypothalamus that stimulates the anterior pituitary to release FSH and LH.
What is FSH?
A hormone released by the anterior pituitary that stimulates Sertoli cells in the seminiferous tubules to promote spermatogenesis.
What is LH?
A hormone released by the anterior pituitary that stimulates interstitial cells in the testes to produce testosterone.
What are interstitial cells?
Cells located next to the seminiferous tubules in the testes that produce testosterone when stimulated by LH.
What are Sertoli cells?
Cells within the seminiferous tubules that support spermatogenesis; also known as sustentacular cells.
What is ABP (Androgen Binding Protein)?
A protein released by Sertoli cells that binds to testosterone, keeping its levels high near developing sperm cells.
What is spermatogenesis?
The process of sperm production, promoted by FSH and testosterone.
What is testosterone's role in negative feedback?
Rising levels of this hormone have a negative feedback effect on the hypothalamus, reducing GnRH secretion.
What is inhibin?
A hormone produced by Sertoli cells that inhibits GnRH and FSH secretion, decreasing spermatogenesis.
What are male secondary sex characteristics?
Characteristics that develop during puberty under the influence of testosterone, such as hair growth in specific areas, larynx enlargement, and increased muscle mass.
List some specific male secondary sex characteristics.
Includes hair growth (facial, armpit, pubic), larynx enlargement (voice deepening), thicker/oilier skin, denser bones, increased skeletal muscle mass, and increased sex drive.
Why do skeletal muscles increase metabolic rate?
Skeletal muscles consuming a lot of energy, leading to an increased basal metabolic rate.
What two factors can trigger the shutoff of the male reproductive hormone system?
High testosterone levels and high sperm count.