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Physiologic Events Related to Aging
Heart disease, pulmonary insufficiency, diabetes, obesity, substance abuse, and depression
Chronic Conditions
Arthritis, heart disease, decreased sensory perception, bone disorders, and diabetes
Prone to antibiotic resistant infections
Polypharmacy-related
Risk to Benefit
Drug Absorption
Reduced number of receptor sites
Changes in affinity to receptors
Have less gastric acid = increased pH = delayed absorption:
More N/V
Poor circulation
Asymptomatic
Still need to take the medication even when they have no symptoms — the medication is often the REASON for no symptoms, but patient may not full comprehend
Low Dosing
“Take 1-2 tablets” — always start with 1 to see reactions and possible adverse effects