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reasons for noninvasive arterial testing
evaluate: arterial disease, pulsatile masses, suspected arterial trauma, angioplasty/stent placement. baseline study before surgery reconstruction, postoperative follow-up, aid in diagnosis of occlusions, supplement clinical judgement
lower extremity duplex imaging
aorta through entire limb
upper extremity duplex imaging
innominate through entire limb
limitations of lower extremity imaging
no visualization of iliacs because of bowel gas or obesity, shadowing from calcs, imaging of popliteal trifurcation/anomalies, difficulty evaluating lesions distal to stenosis because of low velocities
abnormal color findings include:
aliasing, reduced flow channel, color bruit
normal spectral analysis findings:
PSV does not increase, normal, high-resistance spectral waveform, triphasic
velocity ratios
can be used to help classify disease severity
3 major waveform changes - signs of disease
increase in PSVs >100%, spectral broadening and turbulence, loss of reversal of flow
greater than or equal to 50% stenosis
PSV velocity greater than or equal to 2
greater than or equal to 70% stenosis
PSV velocity ratio greater than or equal to 3
suggest a severe stenosis
PSV > 300 cm/s
distal to a hemodynamically significant stenosis
more low resistance flow characteristics, delayed rise to peak systole
proximal to an occlusion
very high resistance pattern, antegrade flow component only during systole, no flow during diastole
contrast arteriography
gold standard for diagnosis of arterial stenosis, can be used when duplex imaging is limited
treatments for PAD
aim to decrease patient symptoms and improve prognosis by preventing the risk of further cardiovascular events, 3 types: medical management/conservative, endovascular, surgical
management/conservative treatment for PAD
control risk factors, exercise, pharmaceutical agents
endovascular treatment for PAD
revascularize limbs, endovascular procedures: angioplasty, endografts, atherectomy, thrombin injections
surgical treatment for PAD
most common: bypass graft surgery, thrombectomy, endarterectomy
endarterectomy
cut open the vessel and clean it out
angioplasty
uses a balloon-tipped catheter to open a blocked blood vessel and improve blood flow
atherectomy
a procedure that utilizes a catheter with a sharp blade on the end to remove plaque from a blood vessel
stent
a tiny expandable mesh tube that can be inserted into a blocked passageway to keep it open
prosthetic (synthetic) bypass graft
made of various manufactured materials (PTFE, dacron), associated with poor long-term patency rates
autogenous vein
preferred graft material, better long-term patency rates, must be carefully monitored in short term for early complications and failure
autogenous: in situ bypass graft
vein being used for bypass is left in its original anatomic position - usually the great saphenous vein, branches must be ligated, valves must be lyzed to allow blood flow downward, large end of vein anastomosed to large end of artery; small end of vein anastomosed with small end of artery (better size match)
autogenous: orthograde
involves lyzing valves
autogenous: retrograde
involves “flipping” the vein; valves do not need to be removed, large end of vein now anastomosed to small end of artery
bypass graft failure within 30 days
retained valve or valve leaflet, intimal flap, suture defect, graft entrapment due to improper positioning, thrombosis
bypass graft failure between 1 and 24 months
Myointimal hyperplasia can develop creating stenosis, stenosis at proximal or distal anastomosis - most common cause of graft revision in this postoperative period
bypass graft failure after 24 months
progression of atherosclerotic disease in inflow or outflow vessels, aneurysmal dilation (conduit or anastomotic site - where they connect)
retained valves
valve or valve remnants that remain due to incomplete valve disruption during surgery, large remnants or valve leaflets can produce flow-limiting stenosis, appears as bright echoes within graft lumen
myointimal hyperplasia
rapid proliferation of cells into intimal layer, can occur any point along bypass conduit, typically occurs in areas where vein has sustained injury or valve sinus, can result in stenosis
normal velocities in bypass graft
typically below 150 cm/s
abnormal velocities in bypass graft
PSV > 180 cm/s
greater than or equal to 50% stenosis in bypass graft
PSV velocity ratio of 2, PSV 180-300 cm/s
greater than or equal to 75% stenosis in bypass graft
PSV ratio of 3.5 and PSV > 300 cm/s
peripheral arterial aneurysms
most commonly present in the popliteal artery, most common cause for pseudo - puncture or trauma to the wall, not likely to rupture, can be limb threatening due to distal embolization which occurs in approx. 35% of cases left untreated
pseudoaneurysm
perivascular collection that communicated with artery or graft and has presence of pulsating blood entering collection, track neck of variable length connects native vessel to collection, can be unilocular or multilocular
treatment for pseudoaneurysms
compression therapy, US-guided thrombin injection, surgery