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Water
most indispensable of all nutrients because we can only survive a few days without it
how much of our body weight is made of water?
60%
Water functions
Transport vehicle for nutrients and wastes, universal solvent, body cleansing agent, lubricant for joints, protection for sensitive tissue, and maintenance of body temperature
Thirst
Pituitary gland signaled to release hormone to kidney to shift water back into blood (decreased urine output)
Symptoms of dehydration
thirst > weakness > exhaustion >delirium > lead to death
Water intoxication
Dilution of body fluids due to excessive intake of plain water
DRI meets ___ of day's need for water
~80%
How many cups of fluid does a male or female need?
male: 13 cups of fluid from beverages and water
female: 9 cups
Electrolytes
compounds that partly dissociate in water to form ions
7 major minerals
calcium, phosphorus, potassium, sulfur, sodium, chloride, magnesium
Trace minerals (9)
Iodine, iron, zinc, copper, selenium, fluoride, chromium, manganese, molybdenum
Which minerals are electrolytes
Sodium, Potassium, Chloride, and serve to maintain water balance in cells and blood
Na and K purposes in the body
used in muscle contractions and nerve transmission
Which minerals function for maintaining and developing body structures? (5)
Ca, P, Mg, F, Zn
Minerals that contribute to structure of DNA, RNA, phospholipids, and ATP
Phosphorus
Which contribute to Protein structure?
Fe, Zn, Ca, Se, I
Which contribute cell signalling and communication?
Ca, Na. Ca moves across cells as a messenger, stimulating proteins and cell activity
Contribute to Antioxidant defence (5)
Zn, Cu, Mn, Se, S
Functions of Calcium
Transport of ions over cell membranes, nerve transmission, muscle contractions, blood clotting, secretion of hormone, and bone structure
Food sources for calcium (4)
milk products, some leafy greens, calcium set tofu, canned sardines
how does the body adapt when calcium concentration is low?
mobilize Ca from bone, increase absorption of Ca by small intestine, and preventing calcium loss from the kidneys
Peak bone mass
Highest attainable bone density developed by late 20's to early 30's
when does one begin to lose bone mass?
40years old but loss can be minimized by taking in lots of calcium in kid and adolescent years.
Calcium deficiency
Osteoporosis - weak brittle bones and fractures
Function of phosphorus
maintenance of acid base balance, in RNA and DNA, metabolism of energy containing nutrients, help enzymes and vitamins take energy from nutrients, and present in some proteins
Where is most phosphorus stored?
bones and teeth
Deficiency of phosphorus
very rare but causes muscular weakness and bone pain
Phosphorus toxicity
calcification of soft tissue (kidney's)
Food sources of phosphorus (3)
milk products, canned salmon, and lean beef
Functions of Magnesium
assists with operation of enzymes, release and use of energy from nutrients, metabolism of other minerals, relaxes muscles** (opposite of Ca), and promotes resistance to tooth decay
where is magnesium stored?
50% in bones
How does your body adapt when Mg intake is low?
releases Mg from bones, and kidneys conserve magnesium (less excretion)
Magnesium deficiency
weakness, confusion, extreme uncontrollable muscle contractions (heart), hallucinations, growth failure, swallowing difficulties
Magnesium toxicity
rare (through supplements only) Diarrhea, dehydration, pH imbalance
Food sources for magnesium
legumes, cooked spinach, bran, oysters. (easily washed and peeled away, unprocessed foods better)
Function of Sodium
chief ion used to maintain fluid volume outside cells, maintenance of acid-base balance, essential for muscle contractions and nerve transmission
1g of salt has ____sodium
400mg
sodium deficiency
rare but cause muscle cramps, mental, loss of appetite
Sodium toxicity
hypertension (high blood pressure)
Excessive sodium may cause...
more calcium excretion, and stress a weakened heart and aggravate kidney problems
who is effected by sodium the most?
those with diabetes, hypertension, kidney disease, african, family history, over 50 years old
DASH (Dietary Approaches to Stop Hypertension)
increasing intake of fruits and vegetables, with moderate amounts of nuts, fish, whole grains, and low fat dairy
Potassium function
chief positive ion used to maintain fluid volume inside cell, maintenance of electrolyte balance, critical to maintaining heart beat.
Relationship between potassium and dehydration
dehydration causes potassium loss from inside cells, and when brain cells lose potassium, it no longer notices the need for water.
Potassium deficiency
muscle weakness, paralysis, confusion, heart failure, worsen hypertension, poor glucose tolerance, accelerate Ca loss, and increase likelihood of kidney stones
Potassium Toxicity
(usually through supplements) muscle weakness, vomiting, extreme can stop heart
Food sources for potassium
Fresh whole foods, fruits, vegetables, legumes
Chloride functions
help sodium maintain fluid, electrolyte, and acid-base balance, and part of HCl so protein digestion in stomach
Sources of Chloride
naturally occurring in salt (NaCl), no known diet lacks chloride
Sulfate functions
synthesis of important sulfur containing compounds (a.a's that form proteins in skin, hair, and nails)
recommended intakes and deficiency for sulfate?
No recommended intake, and deficiency is not seen
Sulfate toxicity
from water, may cause diarrhea or damage to colon
Iodine function
Part of thyroxine (thyroid hormone, and regulates basal metabolic rate (BMR))
Sources of iodine
seafood, eggs, foods grown in iodine rich soil
Basal Metabolic Rate (BMR)
how much we metabolize while doing nothing
Iodine Deficiency
Thyroid gland enlarges (goiter), sluggishness, weight gain, Cretinism (during pregnancy), mental retardation
Iodine toxicity
also enlarges thyroid gland, and poisonous
Iron functions
part of hemoglobin (RBC) and myoglobin (muscle) so oxygen transport, needed for energy metabolism
do vegetarians need more iron? if so how much?
yes, 1.8x more
Iron deficiencies
iron deficiency anemia (small light colored RBC (microcytic), poor oxygen delivery to tissues
Iron deficiency symptoms
weakness, headaches, intolerance to cold, inability to attention, pica (weird cravings)
what can low iron cause?
parasitic infections, and daily blood loss
iron toxicity
protected by low absorption, intestinal cells trap some Fe and shed in feces
Iron overload
Hemochromatosis - genetic disease, intestine absorbs excess Fe
Symptoms of iron overload
Fatigue, mental depression, abdominal pain, tissue damage, liver failure
Acute poisoning
#1 cause of fatal accidental poisonings for children <6 years old
How much iron is absorbed from meat, poultry, and fish?
~23% heme iron
Factor MFP (Meat, Fish, Poultry)
enhances absorption of nonheme in food eaten at same or later time
How much nonheme iron is absorbed from animal and plant foods?
2-20% depending on iron stores and dietary factors
What factors increase nonheme absorption and what factors decrease?
increase: vitamin C, and MFP factor.
Decrease: tea, coffee, Ca, P, phytates, Fibre
is heme iron only found in certain foods? if so which foods?
yes only in meats
Zinc functions
Works with every protein in the body, makes heme in hemoglobin, assists pancreas with digestive functions, metabolize energy yielding nutrients, important for wound healing, reproduction, gene expression, behaviour, and immune function
Food sources of Zinc
meats, shellfish, poultry, milk, and some plant sources (not absorbed well).
when does zinc deficiency occur and what's special about zinc deficiencies
occurs when fibre and phytates bind zinc, but even mild deficiency causes imbalances
zinc deficiency causes
irregular digestive functions, diarrhea, impaired immune system, adverse effects on growth
Zinc toxicity
Loss of appetite, impaired immunity, death, blocks copper and iron absorption
Osteoporosis
a reduction in bone mass of older people, where bones become fragile and porous. (fractures develop later in life but osteoporosis silently develops earlier
types of sectioned bone
cortical bone, trabecular bone
cortical bone
ivory like dense bone that forms the outer shell of bone and shaft of long bones
trabecular bone
web like, lattice of calcium containing crystals (strength and Calcium Bank)
When do the two types of bones begin losing its structure?
trabecular: begins in mid 20's
Cortical: begins around 40 years old
What are risk factors of osteoporosis
Gender, increased age, family history, poor dietary calcium and vitamin D intake, estrogen deficiency, ethnic background, lack of physical activity, being underweight, smoking and alcohol abuse
how to diagnose osteoporosis
x-rays (DEXA) or ultrasound (bone scan)
treatments for osteoporosis
estrogen therapy but may increase risk of heart disease and breast cancer
3 forms of calcium supplements and corresponding absorption rates
calcium compounds - well absorbed
Ca mixtures with other compounds - not absorbed well
Powdered Ca-rich materials - not absorbed well
Calcium compound examples
CaCO₃, Calcium citrate/gluconate/hydroxylate
Mixture of Ca with other compounds examples
Ca Carbonate mixed with MgCO₃
Powdered Ca-Rich materials
bone meal, powdered bone, oyster shell
how to test absorbability and how to maximize absorbance
vinegar test, and take lower doses 2-3 times/ day vs 1 dose
Calcium carbonate absorption vs Calcium glutamate
40% vs 9%