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three types of vaccines
killed, modified live and live
killed vaccines
contains a protein or piece of intended pathogen that can stimulate an immune response but not a disease state (weak immune saturation)
- unable to replicate inside body
- usually the safest type
- dependent on additives present in vaccine to help stim the immune response
modified live vaccines
comprised of naturally occurring pathogen but modified in that it cannot cause disease but allows for immune stimulation
- can replicate in host
- more rapid onset of immunity
- can cause false positves
live vaccines
weakened form of the pathogen that can cause disease with the intention that the severity is limited
- very powerful and strong
Feline core vaccines
FRCCP (feline distemper)
Rabies
what does FRCCP contain
feline rhinotracheitis
feline calicivirus
chlamydia
feline panleukopenia virus
non-core feline vaccines
feline leukemia virus (FELV)
feline immunodeficiency virus (FIV)
what type of vaccine is FRCCP vaccine
modified live
how often is FRCCP given
every 3-4 weeks from 6weeks to 16-20 weeks then 1 year booster after initial series
good for 3 years there after
what the the FRCCP vaccine give cross protection with
canine parvovirus
where is FRCCP given
Right front limb
what type of virus is Feline Viral Rhinotracheitis
herpesvirus
Feline Viral Rhinotracheitis transmission
direct (touch) and indirect (droplets and fomites)
- saliva and ocular discharge
will felines carry Feline Viral Rhinotracheitis for life
yes it is a latent carrier disease
clinical signs of Feline Viral Rhinotracheitis
major for upper respiratory signs
- sneezing and nasal discharge
#1 cause of conjunctivitis
- blepharospasm
- clear to purulent discharge
- keratitis
- corneal ulcers (coreal sequestrum)
Feline Viral Rhinotracheitis digonostics
PCR test
Feline Calicivirus is transmitted how
direct and indirect
oral, nasal, and ocular secretions
Feline Calicivirus clinical signs
sneezing
nasal discharge
conjuctivitis
**oral and lingual ulcers**
drooling
Feline Calicivirus diganositcs
PCR test
Feline Chlamydia transmission
direct contact and the bacteria does not survive well outside body
how is Feline Chlamydia shed
rectal and vaginally
Feline Chlamydia symptoms
conjunctivitis
nasal discharge
sneezing
possible pneumonia
Feline Calicivirus diganositics
PCR test
what type of disease is Feline Panleukopenia Virus
parvovirus
Feline Panleukopenia Virus transmission
direct and indirect via urine, fecal or nasal secretions
Feline Panleukopenia Virus vector
fleas
how long can Feline Panleukopenia Virus live outside body
up to one year
Feline Panleukopenia Virus symptoms
Diarrhea
panleukopenia -> low white blood cells
anemia -> low RBC
cerebellar hypoplasia in kittens b/c the cerebellum is effected
how often is Feline Rabies given
kittens at 12-16 weeks with a one year booster after the subsequent are good for 3 years
what kind of vaccine is Feline Rabies
Recombinant live with canarypox virus with Rabies DNA incorporated
where is rabies give
Right rear limb
Feline Leukemia Virus (FELV) is most common for what cats
outdoor cats
Feline Leukemia Virus vaccine type
recombinant live canarypox vaccine
is Feline Leukemia Virus for life
yes and can be given to other cats
what type of disease is feline leukemia virus
retrovirus
transmission of Feline Leukemia Virus
direct and indirect through nasal, saliva, urine, feces and milk
- allogrooming
Feline Leukemia Virus signs
- cancers
- immune deficiency
- blood disorders
- lymphadenopathy (swollen lymph nodes)
FIV vaccine issues
not commercially available and does not offer great immunity
can cause FISS (feline injection site sarcoma)
what type of disease is FIV
retrovirus
can FIV be given from mom to offspring
yes and kitten can survive it
FIV life expectancy
short lived
three phases of FIV
Acute, Asymptomatic, Progressive
what is Feline Injection Site Sarcoma (FISS)
aggressive and invasive mass that is from poor injection practice
ways to reduce FISS
give vaccines in distal limbs or ventral abdomen
purpose of feline fecal float
to diagnose certain intestinal parasites by identifying parasitic eggs via specific gravity
solutions used for fecal floats
zinc sulfate or sodium nirtate
goal specific gravity
1.2-1.3
why cant you say a fecal float is negative
certain eggs might have a lower specific gravity which would cause them to sink and not show up on the slide
what is Eimeria
a parasite in herbivores poop that can show that your dogs eats other animals crap
common feline parasites
Hookworm (zoonotic)
Roundworm (zoonotic)
Whipworm
Tapeworm (zoonotic)
vertical transmission
parent to offspring
paratenic host
optional intermediate host
roundworm pathogen name and life cycle
toxocara
Infected animal → sheds eggs → matures into L3 larval stage → picked up by host
roundworm transmission
vertical, fecal, oral, foodborne
hookworm tramsission
transdermal
hookworm pathogen name and life cycle
ancylostoma
Infected animal → sheds eggs → rhabditiform larvae → filiform larvae (L3) → transdermal infection of new host
whipworm tramsission
fecal oral
issue with whipworms
very resistant to everything
whipworm life cycle
infected animal → sheds eggs → egg maturation → consumed by new host
tapeworm tranmission
fleas
tapeworm treatment
praziquantel
tapeworm life cycle
Animal ingests infected flea → larval stage develops in GI tract → egg packets shed → flea picks up eggs → new host picks up the infected flea
tapeworm pathogen
Dipylidium caninum
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