DISPENSING 2 LEC M2L3 - Drug-Herb Interactions

Increases risk of bleeding

[Drug-Herb Interactions] Chamomile + Warfarin and other anticoagulants

Prolongs sedation

[Drug-Herb Interactions] Chamomile + Phenobarbital, Barbiturates, Other sedatives

Reduces Fe absorption

[Drug-Herb Interactions] Chamomile + Iron

Increases risk of liver damage

[Drug-Herb Interactions] Echinaceae (Immunostimulant) + Drugs causing liver damage eg Anabolic steroids, Amiodarone, Methotrexate, Ketoconazole

Increases risk of bleeding

[Drug-Herb Interactions] Feverfew (used for Migraine) + Warfarin and other anticoagulants

Increases heart rate and blood pressure

[Drug-Herb Interactions] Feverfew (used for Migraine) + Ergotamine and other migraine drugs

Reduces Fe absorption

[Drug-Herb Interactions] Feverfew (used for Migraine) + Iron

Increases risk of bleeding

[Drug-Herb Interactions] Garlic + Warfarin and other anticoagulants

Intensifies hypoglycemic effects

[Drug-Herb Interactions] Garlic + Insulin, OHAs

Increases risk of bleeding

[Drug-Herb Interactions] Gingko + Warfarin and other anticoagulants

Reduces effects of anticonvulsants

[Drug-Herb Interactions] Gingko + Phenytoin

Intensifies antidepressant effect and increases side effects such as HA, tremors, and manic episodes

[Drug-Herb Interactions] Gingko + MAO inhibitors

Increases risk of bleeding

[Drug-Herb Interactions] Ginger + Warfarin and other anticoagulants

Increases risk of bleeding

[Drug-Herb Interactions] Ginseng + Warfarin and other anticoagulants

Increases side effects

[Drug-Herb Interactions] Ginseng + Corticosteroids, Estrogen Replacement Therapy, MAO inhibitors

Reduces effectiveness

[Drug-Herb Interactions] Ginseng + Opium and its derivatives

Increases drug serum level because of enzyme inhibition

[Drug-Herb Interactions] Grapefruit + Most drugs

Negates anti-arrythmic effect by increasing risk of abnormal heart rhythm

[Drug-Herb Interactions] Licorice + Anti-arrhythmic

Increases risk of digoxin toxicity by lowering potassium levels through increased urine output

[Drug-Herb Interactions] Licorice + Digoxin

Increases diuresis because of K loss

[Drug-Herb Interactions] Licorice + Diuretics

Intensifies antidepressant effect and increases side effects such as HA, tremors, and manic episodes

[Drug-Herb Interactions] Licorice + MAO Inhibitors

Reduces anti-anxiety effect and increases drowsiness

[Drug-Herb Interactions] St. John's Wort + Benzodiazepines

Cyclosporine

[Drug-Herb Interactions] St. John's Wort + Reduces immunosuppressant effect by reducing blood levels of cyclosporine

Reduces effectiveness of digoxin by reducing blood level

[Drug-Herb Interactions] St. John's Wort + Digoxin

Reduces blood level therefore reduce effectivity

[Drug-Herb Interactions] St. John's Wort + Indinavir

Increases risk of sun sensitivity

[Drug-Herb Interactions] St. John's Wort + Photosensitizing drugs e.g.: Omeprazole, Piroxicam, Sulfonamides

Prolong sedation time

[Drug-Herb Interactions] Valerian + Anesthetics

Intensifies effect causing excessive sedation

[Drug-Herb Interactions] Valerian + Barbiturates