DNA Replication

DNA Replication

The production of a new strand of DNA with base sequences identical to existing DNA strand

Semi conservative

Two strands of the double helix separated and both strands used as templates

Replication fork

The site at which the copying is actively occurring

Hydrogen bonds

Complementary bases from —— bond that stabilize the structure

Helicase

Ring shaped protein that separates the strands of dna by breaking hydrogen bonds between the base pairs

DNA Polymerase

Assembles new strands of DNA using original as templates, adds complementary base pairing as it moves down the strand

5’ - 3’

Direction of DNA Polymerase

DNA Ligase

Builds phosphodiester bonds between nucleotides (5’ - 3’)

Leading strand

Read by polymerase continuously

Lagging strand

Okazaki fragments started at primers, leads to discontinuous replication