DNA Replication
The production of a new strand of DNA with base sequences identical to existing DNA strand
Semi conservative
Two strands of the double helix separated and both strands used as templates
Replication fork
The site at which the copying is actively occurring
Hydrogen bonds
Complementary bases from โโ bond that stabilize the structure
Helicase
Ring shaped protein that separates the strands of dna by breaking hydrogen bonds between the base pairs
DNA Polymerase
Assembles new strands of DNA using original as templates, adds complementary base pairing as it moves down the strand
5โ - 3โ
Direction of DNA Polymerase
DNA Ligase
Builds phosphodiester bonds between nucleotides (5โ - 3โ)
Leading strand
Read by polymerase continuously
Lagging strand
Okazaki fragments started at primers, leads to discontinuous replication