Suffix for Drugs on NCLEX

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Last updated 4:49 AM on 7/9/26
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75 Terms

1
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-cycline

Tetracyclines

Broad-spectrum abx

Ex: doxycycline

**avoid anti-acids and dairy products; use sunscreen and protective clothing; affects teeth (brown, speckled stain)

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-thromycin

Macrolide abx

Broad-spectrum

Ex: Azithromycin, Clarithromycin, Erythromycin

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sulf-

Sulfonamides

Abx

Ex: sulfamethoxazole

4
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cef-, ceph-

Cephalosporins

Broad-spectrum abx

Ex: cephalexin, cefepime, ceftriaxone

**report allergies to penicillin and observe for anaphylaxis

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-cillin

Penicillins

Ex: amoxicillin (broad-spectrum)

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-micin, -mycin

Aminoglycosides & macrolides

Abx

Ex: gentamicin, tobramycin

**report tinnitus, vertigo, hearing loss; drink plenty of fluids; give when penicillin is contraindicated

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-floxacin

Fluoroquinolones

Broad-spectrum abx

Ex: ciprofloxacin, levofloxacin

8
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-azole

Antifungals

Ex: fluconazole

9
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-caine

Local anesthetic

Ex: lidocaine

10
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-barbital

Barbiturates (CNS depressants) (sedative, anticonvulsant)

Ex: phenobarbital (seizure control)

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-zolam, -zepam

Benzodiazepines (anxiolytics)

Relieve anxiety, muscle tension, and panic

Ex: lorazepam, diazepam, alprazolam

12
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-done, -one

Opioids

Pain

Ex: oxycodone

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-profen

NSAIDs

Relieve pain, reduce fever, decrease inflammation

Ex: ibuprofen

14
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Aspirin, Bismuth Subsalicylate

Salicylates (class of NSAIDs)

Relieve pain, reduce fever, decrease inflammation

15
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Acetaminophen, Ketorolac, Celecoxib, Naproxen

Nonsalicylates (NSAIDs without the salicylate)

Relieve pain, reduce fever, decrease inflammation

16
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-vir

Antivirals

Ex: Oseltamivir (Tamiflu)

17
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-clovir

Antivirals (anti-herpes viral agents)

Ex: Acyclovir, Valacyclovir

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-navir

Antiretrovirals (protease inhibitors), for HIV

Ex: ritonavir

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-vudine

Antiretrovirals (nucleoside reverse transcriptase inhibitors), treat HIV and Hepatitis B

Ex: Lamivudine, Zidovudine

20
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-oxetine, -talopram

SSRIs, antidepressants

Ex: Escitalopram, Citalopram, Fluoxetine, Sertraline

21
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-triptyline, -pramine

Tricyclic antidepressants

Ex: Amitriptyline, Imipramine

22
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Phenelzine, Isocarboxazid

MAOIs

Antidepressants

Phenelzine- panic disorder and social anxiety disorder too

Isocarboxazid -MDD

23
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-tadine, -tirizine

H1 antagonists (second-generation antihistamines)

Ex: Cetirizine, Loratadine

24
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-eph-, -zoline

Nasal decongestants

Ex: Phenylephrine, Oxymetazoline

25
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-terol

Short acting beta 2 agonists (bronchodilators)

Ex: albuterol

26
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-phylline

Xanthine derivatives (bronchodilators)

Ex: Theophylline, Dyphylline

27
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-tropium

Cholinergic blockers (anticholinergics), prevent involuntary muscle spasms to open airways

Ex: ipratropium, tiotropium

28
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-zumab, -lukast

Immunomodulators (severe, persistent asthma) & leukotriene modifiers (daily oral meds to prevent airway constriction, inflammation, and excess mucus production)

Ex: Omalizumab, Montelukast

29
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-glitazone

Thiazolidinediones

Antidiabetic

Ex: Pioglitazone

30
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-gliptin

Antidiabetic, DPP-4 inhibitors

Ex: Sitagliptin, Linagliptin

31
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-pril

ACE Inhibitors, Antihypertensive

Ex: Lisinopril, Enalapril

Watch for hyperkalemia, dry cough, and angioedema

32
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-olol

Beta Blockers, antihypertensive, and reduces HR

Ex: Metoprolol, Atenolol, Propranolol, Carvedilol

**assess pulse and BP prior; blood sugar is masked when low (hypoglycemia)

33
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-sartan

ARBs (angiotension recpetor blockers)

Antihypertensive, treat HF, and CKD

Ex: Losartan, Valsartan

34
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-pine, -amil

Calcium channel blockers

Antihypertensive, angina, and arrhythmias

Ex: Amlodipine, Nifedipine, Diltiazem (slow HR, for Afib and angina too)

35
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-vaptan

Antihypertensive

Block ADH in the kidneys (excrete free water without losing electrolytes)

Ex: Tolvaptan, Conivaptan

36
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-osin

Alpha 1 blockers (blocks norepinephrine)

Antihypertensive & for BPH

Ex: Tamsulosin (BPH), Prazosin

37
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-ide, -semide

Loop diuretics (expel sodium, potassium, and water) (potassium-wasting)

Antihypertensive

Ex: Furosemide, Torsemide, Bumetanide

**diet increase K+; daily weight; take with or after meal in the AM; no smoking and alcohol

38
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-thiazide

Thiazide diuretic

Antihypertensive

Ex: Hydrochlorothiazide (HCTZ)

39
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-actone

Potassium-sparing diuretic

Antihypertensive

Ex: Spironolactone

40
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-tidine

H2 blockers

Reduce production of stomach acid to treat GERD, heartburn, and stomach ulcers

Ex: Famotidine, Cimetidine

41
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-prazole

PPI

Reduce production of stomach acid to treat GERD, heartburn, and stomach ulcers

Ex: Omeprazole, Esomeprazole, Pantoprazole, Lansoprazole (EXCEPT Aripiprazole)

**give on empty stomach before meals, avoid alcohol, ASA, NSAIDS, smoking and caffeinePPIs

42
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-statin

Antihyperlipidemics

HMG-CoA reductase inhibitor

Ex: Atorvastatin, Rosuvastatin

43
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-xaban

Anticoagulant

Factor Xa inhibitors

Ex: Apixaban, Rivaroxaban

44
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-parin

Low-molecular-weight heparins

Anticoagulant

Ex: Enoxaparin, Dalteparin

**report unusual bleeding, soft toothbrush and electric razors, antidote is protamine sulfate

45
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-teplase

Thrombolytics (clot busters)

Ex: Alteplase

**maintain bedrest; contraindicated in clients w/ active internal bleeding; for MI give within 6h of onset; for CVA give 2-3h of onset; antidote is aminocaproic acid (Amicar)

46
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-arone

Broad-spectrum antiarrhythmic

Potassium-channel blockers

Ex: Amiodarone (ventricular dysrhythmias)

47
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-afil

Phosphodiesterase inhibitor (PDE inhibitor)

Tx of erectile dysfunction

Ex: sildenafil (Viagra)

48
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-sone, -lone

Corticosteroid

Decreases inflammation and normal immune response (immunosuppressive meds)

Ex: Predisone, Dexamethasone, Fluticasone, Prednisolone, Methylprednisolone

**don’t stop suddenly, avoid grapefruit juice and limit caffeine, give with food in the AM to decrease gastric upset

49
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-cort-

Corticosteroid

Decreases inflammation and immune response

Ex: Hydrocortisone

**dont stop suddenly; avoid grapefruit juice and limit caffeine; give with food in AM to decrease gastric upset

50
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-dronate

Biphosphonate, bone resorption inhibitor

Tx and prevention of osteoporosis

Ex: Alendronate

**take in the AM, 30 min before other medication of food and remain upright; engage in weight bearing activites

51
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-setron

Antiemetic, antinauseant

Prevents N/V

Ex: Odansetron

52
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-triptan

Antimigraine

Ex: Sumatriptan

**use only during migraine; avoid alcohol (which aggravates migraines); report chest pain

53
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Metformin

Antidiabetic for Type 2 DM

Take with meals and avoid taking for surgeries and scans using contrast dye

54
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Nitroglycerin

Angina

55
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Gabapentin

Anti-convulsant and for peripheral neuropathy

56
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Methotrexate

Immunosuppressant

57
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Methylergonovine

Prevents PPH

Can’t breastfeed (pump and dump)

58
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Oxytocin (Pitocin)

Induces contractions

Stop if late decelerations appear

59
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Risperidone

Atypical Antipsychotic for schizophrenia

60
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-thyroxine

Thyroid Hormone Replacement

Tx for hypothyroidism and Hashimoto’s

Ex: Levothyroxine

61
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Clopidogrel

Antiplatelet

62
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Lithium

Mood stabilizer for mania in bipolar disorder

>2 LITHIUM TOXICITY

63
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Haloperidol

Atypical Antipsychotic (schizophrenia, mania, aggressive and agitated patient)

- extrapyramidal symptoms (involuntary contractions, tremors, restlessness, rigidity)

- may cause seizures, constipation, dry mouth, agranulocytosis

- monitor for neuroleptic malignant syndrome

64
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Aripiprazole

Atypical antipsychotics (schizophrenia, bipolar disorder, MDD)

- extrapyramidal symptoms (involuntary contractions, tremors, restlessness, rigidity)

- may cause seizures, constipation, dry mouth, agranulocytosis

- monitor for neuroleptic malignant syndrome

65
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Epoetin

Treat anemia by producing more RBCs

66
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Pregabalin

Anticonvulsant and for neuropathic pain (fibromyalgia)

67
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Varenicline

Smoking deterrent

68
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Donepezil

Cholinesterase inhibitors

Dementia patients to help improve memory, thinking, and communication between nerve cells

69
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Rifampin

Abx for TB (both active and latent)

70
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Memantine

Treats moderate to severe Alzheimer’s

71
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Rifampin, Isoniazid, Ethambutol

Abx for TB

72
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Adenosine

SVT

73
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Dutasteride, Finasteride

5-Alpha Reductase inhibitors

BPH

74
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Phenytoin

Anticonvulsant (prevent and control generalized tonic-clonic and focal seizures in epilepsy patients)

75
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Digoxin

Antiarrhythmic (for CHF, A-fib, A-flutter)

Increases cardiac output and slows the rate

- Use caution with diuretic use as they may cause electrolyte abnormalities that can lead to

toxicity

- Signs of toxicity include vision changes (blurred vision, yellow, green vision disturbances)

- Monitor pulse rate for 1 full minute prior to dosing patient (hold for pulse <60)