T cells and C cells binding

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13 Terms

1
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T cells first step:

dendritic cell engulfs a bacterium

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T cells second step:

large molecules of engulfed bacterium are broken down by lysosomes to produce antigenic peptides

3
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T cells third step:

New MHC molecule has been synthesized by endoplasmic reticulum-golgi complex

4
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T cells fourth cell:

antigenic peptides bind to newly formed MHC molecules

5
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T cell fifth step:

antigen is displayed on cell surface bound to MHC moecule-cell is now an antigen-presenting cell(APC)

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Cytotoxic T cells first step:

class I MHC molecules are found on surface of all cells

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Cytotoxic T cells second step:

they are recognized only by cytotoxic(CD8+) T cells

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Cytotoxic T cells third step:

CD8 coreceptor links the two cells together

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Cytotoxic T cells fourth step:

Linked in way, cytotoxic T cells can destroy body cells if invaded by foreign(viral) antigen

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Helper T cell first step:

Class II MHC molecules are found on surface of immune cells with which helper T cells interact: denticity cells, macrophages, and B cells

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Helper T cell second step:

They are recognized only by helper(CD4+) T cell

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Helper T cell third step:

CD4 coreceptor links the 2 cells together

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Helper T cell fourth step:

To be activated, helper T cells must bind with a class II MHC-bearing APC(dendritic cell or macrophage) To activate B cells, helper T cell must bind with class II MHC- bearing B cell with displayed foreign antigen