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T cells first step:
dendritic cell engulfs a bacterium
T cells second step:
large molecules of engulfed bacterium are broken down by lysosomes to produce antigenic peptides
T cells third step:
New MHC molecule has been synthesized by endoplasmic reticulum-golgi complex
T cells fourth cell:
antigenic peptides bind to newly formed MHC molecules
T cell fifth step:
antigen is displayed on cell surface bound to MHC moecule-cell is now an antigen-presenting cell(APC)
Cytotoxic T cells first step:
class I MHC molecules are found on surface of all cells
Cytotoxic T cells second step:
they are recognized only by cytotoxic(CD8+) T cells
Cytotoxic T cells third step:
CD8 coreceptor links the two cells together
Cytotoxic T cells fourth step:
Linked in way, cytotoxic T cells can destroy body cells if invaded by foreign(viral) antigen
Helper T cell first step:
Class II MHC molecules are found on surface of immune cells with which helper T cells interact: denticity cells, macrophages, and B cells
Helper T cell second step:
They are recognized only by helper(CD4+) T cell
Helper T cell third step:
CD4 coreceptor links the 2 cells together
Helper T cell fourth step:
To be activated, helper T cells must bind with a class II MHC-bearing APC(dendritic cell or macrophage) To activate B cells, helper T cell must bind with class II MHC- bearing B cell with displayed foreign antigen