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metformin
MOA:
insulin sensitizer
decrease glucose production
first line drug DM2
use:
decrease BG
decrease hyperglycemia
AE:
lactic acidosis
N/V/D
abd discomfort
Vit B deficiency
teach:
with food
no alcohol
sun protection
sulfonylureas
glipizide , glyburide
MOA:
increase insulin sensitivity, insulin secretion and number receptor
use:
decrease BG
hyperglycemia
AE:
weight gain
teach:
no alcohol
sun protection
sitagliptin
MOA:
slow breakdown GLP-1
increase effects of incretin
use:
decrease BG
hyperglycemia
AE:
well tolerated
teach:
no alcohol
sun protection
well tolerated
DM 2
insulin resistance
develop over time
diet + exercise
lifestyle
decrease weight
no smoke/alcohol