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Fundamentals of Nursing
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Infection
When microorganisms capable of producing disease invade the body
The Spread of Infection: Six Links
Infectious agent → Susceptible host → Portal of entry → Mode of transmission → Portal of exit → Reservoir
Infectious agents
Pathogens
Normal flora that become pathogenic
Reservoir
Where pathogens live and multiply
May be living
Humans, animals, insects
May be nonliving
Food, floors, equipment, contaminated water
Portal of exit
Via
Bodily fluids
Coughing, sneezing, diarrhea
Seeping wounds
Tubes, IV lines Mode of transmission
Contact
Direct: Touching, kissing, sexual contact
Indirect: Contact with a fomite
Droplet: Cough, sneeze
Airborne: Via air conditioning, sweeping
Portal of entry
Eyes, nares, mouth, vagina, cuts, scrapes
Wounds, surgical sites, IV or drainage tube sites
Bite from a vector
Susceptible host
Person with inadequate defense
Four determining factors
Virulence
Organism’s ability to survive in the host’s environment
Number of organisms
Host’ defense
Stages of Infection
Incubation: From time of infection until manifestation of symptoms; can infect others
Prodromal: Appearance of vague symptoms; not all diseases have the stage
Illness: Signs and symptoms present
Decline: Number of pathogens decline
Convalescence: Tissue repair, return to health
Classifications of Infections
By location
Local
Occurs in a limited region in the body (e.g., urinary tract infection)
Systemic
Spread via blood or lymph
Affects many regions (e.g., septicemia)
Classification of Infections by Duration
Acute: Rapid onset of short duration (e.g., common cold)
Chronic: Slow development, long duration (e.g., osteomyelitis)
Latent: Infection present with no discernible symptoms (e.g., HIV/AIDS)
Healthcare-Related Infection
An infection acquired as a result of healthcare
Cost of the healthcare system: $4.5 billion/year
Leading cause of death
Preventable with use of aseptic principles/techniques
Exogenous healthcare-related infection: Pathogen acquired from healthcare environment
Endogenous healthcare-related infection: Normal flora multiply and cause infection as a result of treatment
Lines of Defense Against Infection
Primary defenses
Anatomical features, limit pathogen entry
Intact skin
Mucous membranes
Tears
Normal flora in gastrointestinal (GI) tract
Normal flora in urinary tract
Secondary defenses
Biochemical processes activated by chemicals released by pathogens
Phagocytosis
Complement cascade
Inflammation
Fever Tertiary defenses
Humoral immunity
B-cell production of antibodies in response to an antigen
Cell-mediated immunity
Direct destruction of infected cell by T cells
Factors That Increase Infection Risk
Developmental stage
Breaks in the skin
Illness/injury, chronic disease'
Smoking, substance abuse
Multiple sex partners
Medications that inhibit/decrease immune response
Nurisng/medical procedures
Factors That Support Host Defenses
Adequate nutrition
To manufacture cell of the immune system
Balanced hygiene
Sufficient to decrease skin bacterial count
Not overzealous; causing skin cracking
Rest/exercise
Reducing stress
Immunnization
Preventing Infection: Implementing Medical Asepsis
Medical asepsis
“A state of cleanliness that decreases the potential for the spread of infections”
Promoted through
Maintaining a clean environment
Maintaining clean heads
Following guidelines from the Centers for Disease Control and Prevention (CDC)
Maintaining a Clean Environment
Clean spills and dirty surfaces promptly.
Remove pathogens through chemical means (disinfect).
Remove clutter.
Consider supplies brought to the client room as contaminated.
Consider items from the client’s home as contaminated.
Wash Your Hands
When you arrive in the unit
When you leave the unit
Before and after restroom use
Before and after client contact
Before and after contact with client belongings
Before gloving
After glove removal
Before and after touching your face
Before and after eating
After touching a contaminated article
When you see visible dirt on your hands
Handwashing Guidelines
Wash for at least 20 sec in nonsurgical setting; 2 to 6 min in surgical setting.
Remove jewelry and clean beneath fingernails.
Use a bactericidal solution or use water if hands are visibly soiled.
Use warm water, not hot.
Apply soap to wet hands.
Use friction.
Rinse soap.
Towel or hand dry.
Implementing CDC Guidelines
Standard precautions
Protects healthcare workers from exposure
Decrease transmission of pathogens
Protects from pathogens carried by healthcare workers
Transmission- Based Precautions
Contact precautions
• Pathogen is spread by direct contact.
Sources of infection: Draining wounds, secretions, supplies
Precautions include
• Possible private room
• Clean gown and glove use
• Disposal of contaminated items in room
• Double-bag linen and mark
Airborne precautions
• Pathogen is spread via air currents.
Transmission via ventilation systems, shaking
sheets, sweeping
Precautions include
• Same as those for contact, with addition of special room, special
mask, and mask for patient when transported
Droplet precautions
• Pathogen is spread via moist droplets.
Coughing, sneezing, touching contaminated objects
Precautions include
• Same as those for contact
• Addition of mask and eye protection within 3 ft of client
Protective Isolation
“Protective environment”
• Protects the client from organisms
• Used in special situations with immune-
compromised client population
Precautions include
• Room with special ventilation and air filters; no
carpeting; daily wet-dusting
• Avoiding standing water in the room (e.g.,
humidifier)
• Nurse not assigned to other clients with active
infection
• Standard and transmission-based precautions,
plus mask and other personal protective
equipment (PPE) (to protect patient)
Implementing Surgical Asepsis
Includes
• Creation of a sterile environment
• Use of sterile equipment/supplies
• Sterilization of reusable supplies
• Surgical hand scrub
• Surgical attire
• Sterile gloves
• Sterile field
• Use of sterile technique