Hematologic Neoplasms Flashcards

Flashcards about Hematologic Neoplasms, Leukemia, and Polycythemia Vera

Leukemia

Hematopoietic malignancy with unregulated proliferation of leukocytes

Acute Myeloid Leukemia (AML)

Defect in stem cell that differentiate into all myeloid cells: monocytes, granulocytes, erythrocytes, and platelets; most common nonlymphocytic leukemia

Chronic Myeloid Leukemia (CML)

Mutation in myeloid stem cell with uncontrolled proliferation of cells-Philadelphia chromosome

Acute Lymphocytic Leukemia (ALL)

Uncontrolled proliferation of immature cells from lymphoid stem cell; most common in young children

Chronic Lymphocytic Leukemia (CLL)

Common malignancy of older adults derived from a malignant clone of B lymphocytes

"B symptoms"

A constellation of symptoms including fevers, drenching sweats (especially at night), and unintentional weight loss; seen in CLL

Polycythemia Vera

Cancer of the RBCs leading to massive numbers of RBCs and leukocyte/thrombocyte overproduction