Layers of Epidermis (Superficial to Deep)

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Most Superficial (1) to Deep (5)

Last updated 5:01 AM on 6/26/26
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5 Terms

1
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Stratum Corneum (1)

  • Multiple layers of dead, flattened, keratin-filled cells

  • Provides waterproofing and resistance to abrasion

2
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Stratum Lucidum (2)

Thin, clear layer present only in thick skin (palms and soles)

3
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Stratum Granulosum (3)

  • Cells accumulate keratin granules and lipid-rich secretions

  • Formation of the epidermal water barrier begins here

4
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Stratum Spinosum (4)

  • Cells connected by desmosomes, providing strength

  • Active keratin production occurs

5
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Stratum Basale (5)

  • Germinativum

  • Single layer of rapidly dividing cells

  • Contains stem cells and melanocytes