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antidepressants
affects levels of neurotransmitters including serotonin
SSRIs
increases level of serotonin at the synapse by preventing reuptake. fluoxetine is an example
combination treatment
SSRIs combined with psychological therapies like CBT and with other drugs
alternative to SSRIs
clomipramine and SNRIs
SNRIs
serotonin and noradrenaline reuptake inhibitors. different class of antidepressants, increases levels of serotonin and noradrenaline
clomipramine - tricylic antidepressant
acts on systems including the serotonin system and works in the same way as SSRIs. however it has more severe side affects
research support for biological treatments for OCD - soomro et al
reviewed 17 studies comparing SSRIs to placebos in treating OCD. all studies showed significantly better outcomes in SSRIs compared to placebos.
research support - nestadt, review of twins
68% of MZ twins share OCD compared to 31% of DZ twins. supports the genetic explanation of OCD
strength of biological treatments for OCD - cost-effective and non-disruptive
drugs are cheap compared to psychological treatments and they're not disruptive to people's lives like therapy sessions are
limitation of biological treatments for OCD - serious side effects
these drugs can cause side effects like indigestion and blurred vision. this is particularly prominent in the tricyclic clomipramine
limitation of biological treatments for OCD - bias in evidence
some psychologists believe there is bias in evidence as researchers are often sponsored by drug companies that may selectively publish positive outcomes.