Specific Liver Function Test, Results, and Associated Abnormalities

decreased albumin

chronic liver disease & cirrhosis

increased ALP

cirrhosis, extrahepatic biliary obstruction, gallstones, hepatitis, metastatic liver disease, & pancreatic carcinoma

increased ALT

biliary tract obstruction, hepatitis, hepatocellular disease

obstructive jaundice

increased AST

cirrhosis, fatty liver, hepatitis, & metastatic liver disease

increased gamma-Glutamyl transferase

diffuse liver disease & posthepatic obstruction

increased LDH

cirrhosis, hepatitis, & obstructive jaundice

increased serum bilirubin

unconjugated (direct) bilirubin: acute hepatocellular disease, conjugated (indirect) bilirubin: biliary tract obstruction, total bilirubin: cirrhosis, hepatitis, and other liver cell diseases

PT

prolonged PT: metastasis of the liver and hepatitis

shortened PT: extrahepatic duct obstruction

increased AFP

hepatocellular carcinoma (hepatoma), & hepatoblastoma