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Vocabulary flashcards for myocardial muscle tissue physiology, covering cardiac myocyte structure, function, electrical properties, and the cardiac cycle.

Biology

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23 Terms

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Cardiac Myocytes

Relatively short muscle cells with branches that connect to one another, unlike skeletal muscle cells.

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Intercalated Discs

The junctions where one cardiac muscle cell connects to a neighboring cell, characterized by desmosomes and gap junctions.

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Desmosomes

Protein junction molecules within intercalated discs that resist physical stress and prevent cells from tearing apart.

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Gap Junctions

Protein junction molecules within intercalated discs that allow cells to share nutrients, wastes, and electric current (action potentials).

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Striations

Stripes resulting from the spatial arrangement of myofilaments (muscle proteins arranged into myofibrils) in both cardiac and skeletal muscle tissue.

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Myofilaments

Muscle proteins (actin and myosin) arranged into bundles called myofibrils.

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Mitochondria

Organelles that are more abundant in cardiac cells compared to skeletal cells due to the continuous activity and high energy demand of cardiac muscle.

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Myocardium

Two subtypes of cardiac muscle cells: contractile cells and conductive cells.

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Contractile Cells

The majority of cells in the myocardium (over 99%) whose function is to generate muscular force during the cardiac cycle to push blood around.

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Conductive Cells

Less than 1% of the cells in the myocardium whose function is to rapidly conduct electric current from one point to another within the heart.

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Sinoatrial Node (SA Node)

A cluster of connecting conductive cells in the wall of the right atrium that normally generates current first and fires action potentials first.

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Atrioventricular Node (AV Node)

A node at the junction between the atria and the ventricles that is stimulated to fire action potentials when current flows through the atria.

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Fibrous Skeleton of the Heart

A layer of thick fibrous connective tissue that blocks electric signals between the atria and ventricles.

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AV Bundle and Bundle Branches

Connecting branches of conductive cells that pass electric current down the middle of the interventricular septum.

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Purkinje Fibers

Additional conductive cell branches near the apex of the heart that shoot up the lateral edges of the ventricular walls.

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AV Nodal Delay

A brief pause that occurs before the AV node passes on electric current to ensure the timing of the mechanical events of the cardiac cycle is correct.

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Autorhythmic and Pacemaker Cells

Alternate names for conductive cells, indicating their ability to generate current on their own without external stimulation.

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Biological Pacemaker

The part of the heart that fires an action potential first, setting the pace for heart contraction; normally the SA node.

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Pacemaker Potential

The slow depolarization that occurs in conductive cells, allowing them to self-depolarize and set the pace for the heart's contraction.

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Excitation-Contraction Coupling

The process by which firing an action potential stimulates contraction in contractile cells, involving calcium release and binding to troponin.

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Troponin

A regulatory protein on the thin filament that is activated by calcium binding, causing a change in shape and movement of tropomyosin.

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Tropomyosin

A regulatory protein of the thin filament that is moved away from binding sites on actin for myosin by activated troponin.

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Plateau Phase

A phase in the contractile myocyte action potential characterized by a more horizontal part of the curve, resulting from the balance of calcium and potassium ion movement, which prolongs the action potential and prevents muscle twitch summation.