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-cide
Refers to a treatment that kills the targeted microorganism.
-cidal
Indicates that a treatment kills microorganisms.
-stat
Refers to a treatment that stops microbial growth without necessarily killing the microorganisms.
-static
Indicates that a treatment inhibits microbial growth.
Bactericide
A substance or treatment that kills bacteria.
Viricide
A substance or treatment that kills or inactivates viruses.
Fungicide
A substance or treatment that kills fungi.
Bacteriostatic treatment
A treatment that inhibits the growth of bacteria without necessarily killing them.
Fungistatic treatment
A treatment that inhibits the growth of fungi.
Factors affecting -cidal or -static treatments
The type of microorganism, the concentration of the chemical, and the nature of the treatment.
Preference for bacteriostatic over bactericidal
It may be less toxic to humans and better preserves the integrity of treated material.
Use of -static chemicals in plastics
Incorporated into plastics to prevent microbial growth on the surface.
Examples of -static chemicals in products
Children's toys and cutting boards.
Effectiveness of bacteriostatic treatment for infections
It prevents the pathogen from multiplying, allowing the immune system to eliminate remaining microorganisms.
Microbial death curve
A graph used to show the progress and effectiveness of a microbial control treatment over time.
Population behavior during control protocol exposure
A fixed percentage of the population dies over each equivalent time interval.
Usefulness of percentage reduction
More useful than absolute numbers because microbial killing occurs at a constant percentage rate.
Scale used for microbial death curves
A semilogarithmic (semilog) scale.
Reason for plotting microbial death on semilog scale
Microbial death is generally logarithmic, making reduction easier to visualize.
Decimal reduction time (DRT)
The amount of time required for a treatment to produce a 1-log reduction in a microbial population.
Another name for decimal reduction time
The D-value.
Percentage of microorganisms killed during one D-value
90%.
Population change after one D-value
Decreases by one order of magnitude, leaving 10% of the original.
Remaining cells after one D-value from 10⁶
10⁵ cells.
Exposure time impact on microbial control
Longer exposure times generally kill more microorganisms.
Larger starting population treatment duration
Requires more time due to logarithmic microbial death.
Effect of disinfectant concentration on microbial control
Higher concentrations generally kill microorganisms more quickly and effectively.
Temperature effect on microbial control
Higher temperatures generally increase the rate of microbial killing.
Effect of bodily fluids and organic debris on disinfection
Limits contact between the antimicrobial agent and microorganisms, requiring longer or more intense treatment.
Major factors for selecting microbial control method
Exposure time, starting microbial population, microbial susceptibility, concentration or intensity of treatment, and conditions that interfere with contact.