cell and structures 1.01-1.05

where are parietal cells found?

stomach

what do parietal cells do? (2)

secrete HCl and intrinsic factor

where are chief cells found?

stomach - base of gastric glands

what do chief cells do? (2)

secrete pepsinogen and gastric lipase

where are G cells found? (2)

antrum of stomach and duodenum

what do G cells do?

secrete gastrin

where are ECL cells found?

antrum of stomach

what do ECL cells do?

release histamine

what cells are found in the gastric glands from superficial to deep? (6)

- surface mucous-secreting cells

- neck mucous-secreting cells

- stem cells

- parietal cells (acid-secreting)

- chief cells (enzyme-secreting)

- neuroendocrine (G-cells and eneterochromaffin-like cells)

where are enterocytes found?

small intestine

where are paneth cells found?

Crypts of Lieberkuhn - small intestine

what do paneth cells do?

secrete lysozymes to kill bacteria

how can you spot Paneth cells on a slide?

stain bright pink

where are K cells found?

crypts of Lieberkuhn - duodenum mostly and jejunum

what do K cells do?

secrete gastric inhibitory peptide (GIP)

what does GIP do?

stimulates insulin secretion

where are I cells found?

crypts of Lieberkuhn - duodenum mostly and jejunum

what do I cells do?

secrete cholecystokinin (CCK)

what does CCK do? (2)

- stimulates gallbladder contraction

- stimulates pancreatic enzyme secretion

where are S cells found?

crypts of Lieberkuhn - duodenum mostly and jejunum

what do S cells do?

secrete secretin

what does secretin do?

stimulates bicarbonate secretion from pancreas

where are enterochromaffin cells found?

crypts of Lieberkuhn - small intestine

what do enterochromaffin cells do?

release histamine and serotonin

what does serotonin do?

stimulates CFTRs

what doe CFTRs do?

- secrete Cl- ions into lumen

- Na+ and water follow