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What is the layout of the ANS?
The parasympathetic ganglion is very close to the target organ
The preganglionic nerve releases acetylcholine that binds to a nicotinic receptor
The postganglionic nerve releases acetylcholine that binds
to an muscarinic receptor.
What does acetylcholine released from postganglionic fibres bind to?
Acetylcholine released from postganglionic fibres bind to muscarinic (M) acetylcholine receptors
Several subtypes of receptors exist, especially M1, M2 and M3
M1 - CNS effects
M2 - slows heart rate
M3 - contracts bladder and gastro-intestinal tract increases saliva secretion
How many of the 12 cranial nerves carry parasympathetic nerve fibres?
4
What are sacral parasympathetic nevres?
Sacral parasympathetic nerves importantly
innervate the bladder and lower gastrointestinal tract to control micturition and defaecation.