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membrane
separates the inside of the cell from the outside environment
nucleus
A part of the cell containing DNA and RNA and responsible for growth and reproduction
Mitochondria
Powerhouse of the cell, organelle that is the site of ATP (energy) production
ribosomes
site of protein synthesis
endoplasmic reticulum
network of thin tubes transporting newly synthesized proteins
Glia
glue: holds neurons together
astrocyte
type of glial cell:
wraps around synaptic terminal
synthesizes activity for a group of neurons
microglia
type of glial cell:
removes damage and cleans up
Oligrodendrocytes
type of glial cell:
cell that make up the myelin INSIDE CNS
Schwann cell
creates myelin sheath in nerves OUTSIDE CNS
radial glia
guide migration of neurons during embryonic development
cornea
outer surface of eye
- protects eye
- refracts light
iris
colored muscle
- regulates pupil by growing and shrinking to make pupil dilate
pupil
regulates light input
lens
focuses images on retina
ciliary muscle
controls the lens
- muscles attached to the lens that stretch and relax lenses
- as you age, the muscle gets less strong so older people need glasses
fovea
center of vision
- contains most cones
birds have a second fovea
on the side
- makes peripheral vision really good
rodents have a second fovea
on bottom
- makes vision better to watch for predators ABOVE
retina
where light gets processed
- Contains photoreceptors
- transduction occurs at back of retina:
transduction
Converts light to energy to AP
Rods
- 100-120 million
- Sensitive to dim light
- black/white discrimination
- concentrated on the periphery-cannot see details
- Poor detail because many receptors converge their input onto a given ganglion cell
cones
- 4-6 million
- Used for color vision
- Very densely located near the fovea, very few cones in peripheral vision
- Red, green, blue cones
- Good detail because each cone's own ganglion cell sends a message to the brain
in a rod, each ganglion cell is excited by ____________ of rods
thousands
in a cone, each ganglion cell is excited by ______________ cone
one
Photopigments:
Chemicals contained by both rod and cones that release energy when struck by light
photopigment process
- 11-cis retinol bound to proteins called Opsin
- Light converts 11-cis to all-trans retinol
- All-trans activates second messengers within the cell
Human eyes perceive light/color from
400nm to 700nm (wavelengths)
Trichromatic theory (Young-Helmholtz Theory):
color perception occurs through the relative rates of response by 3 kinds of cones
short cone =
blue
long cone =
red
medium cone =
green
Opponent Process Theory:
suggest that we perceive color in terms of paired opposite
- Colors that we cannot perceive at the same time are termed opposing
- Red and green
- Yellow and blue
- White and black
A possible mechanism for the theory is that ganglion cells are excited by one set of wavelengths and inhibited by its opposite
Brightness constancy:
brightness is determined by comparing to nearby objects
Color constancy:
ability to recognize colors despite changes in lighting
Retinex Theory:
V1 cells in the cortex compare info and signals from different parts of the retina to determine color and brightness
- Assumptions based on experiences affect perception
Receptive Field:
part of the visual field hat either excite or inhibit a cell
- For a receptor, point in space from which light strikes it
- For other visual cells, receptive fields are derived from the visual field of cells that either excite or inhibit cells
Ex: ganglion cells converge to form the receptive field of the next level of cells
3 Cellular Layers of the Retinal Ganglion Cell and the LGN
parvocellular
magnocellular
koniocellular
Parvocellular:
Sensitive to color and detail
- in/near fovea
- Small body
- Small receptive field
Magnocellular:
Sensitive to patterns and motion
- Throughout retina
- Large body
- Large receptive field
Koniocellular:
several functions-sensitive to color, shape, patterns, and motion
- Throughout retina
- Small body
- Varied receptive field
Horizontal cells:
type of cell that receives input from receptors and delivers inhibitory input to bipolar cells
- Convert shapes into amacrine cells and ganglion cells in the eyeball
amacrine cells
get info from bipolar cells and send it to other bipolar cells
- enable certain areas to respond
bipolar cells
type of neuron in the retina that receives input directly from the receptor
ganglion cells
type of neuron in the retina that receives input from the bipolar cell
optic nerve
ganglion cell axons that exit through the back of the eye and continue to the brain
- Leaves the retina and travels along the lower surface of the brain
- Ends at either the LGN of the thalamus or hypothalamus and superior colliculus
Superior colliculus:
helps us to quickly shift eyes to stimulus
optic chiasm
where the optic nerve from two eyes meet
- Half axons from each eye ross ino the opposite side of the brain
- Info from temporal half goes to ipsilateral (same) hemisphere
Lateral Geniculate Nucleus (LGN):
primary relay center for visual information received from the retina of the eye (located in thalamus)
- Most ganglion cell axons go in this part of the thalamus
- Some axons go to the superior colliculus and hypothalamus
- Areas that control waking-sleeping schedule
- Sends axons to other parts of the thalamus and visual cortex
- Axons returning from the cortex to the thalamus modify thalamic activity
Lateral inhibition:
reduction of activity in one neuron by activity in the neighboring neurons
- Function = to sharpen borders
- Important for any function in the NS
- In olfaction (smelling), strong stimulus act suppress the response to another that follows close after it due to the inhibition of the olfactory bulb
- In touch, simulation of one spot on the skin weakens the response to stimulation of a beginning sot
- In hearing, inhibition makes it possible to understand speech even with background noise.
The Primary Visual Cortex (V1):
area of the cortex responsible for the first stage of visual processing
- located in occipital cortex aka area V1 or striate cortex
V1 damage
People have no conscious vision, visual imagery and no visual images in their dreams
BUT Adults who lose their vision still have visual imagery and visual dreams
Blind sight:
ability to respond to limited ways to visual info without perceiving it consciously
- Small islands of healthy tissue remain within an otherwise damaged visual cortex, not large enough to provide conscious perception but enough to support limited visual functions
- Thalamus sends visual input to many brain areas including temporal cortex
Simple cell:
type of visual cortex cell that has a receptive field with fixed excitatory and inhibitory zones (ONLY ONE LOCATION)
- The more light shines in excitatory zones, the more the cell responds
- The more light shines in inhibitory zone, the less the cell responds
Complex Cell:
type of visual cortex cell located in areas V1 and V2 that respond to a pattern of light in certain orientation ANYWHERE within it large receptive field
- Responds strongly to stimulus moving a certain direction
End-stopped/hypercomplex cells:
strong inhibitory area at one end of its bar-shaped receptive field
- Same as complex cell but with inhibitory zone like a simple cell
- Responds to bar shaped pattern of light anywhere in its broad receptive field, assuming the bar doesn't extend beyond a certain point
Cells with similar properties group together the visual cortex in columns perpendicular to the surface
Ex: cells in a column might respond to only the left eye, only the right eye, or both eyes equally
- Cells within a column respond best to lines of a single orientation
Feature detectors:
neurons whose responses indicate the presence of a particular feature-shape or direction of movement
If one eye is closed during early development,
the cortex becomes unresponsive to it.
If both eyes are closed,
cortical cells remain somewhat responsive for several weeks, gradually becoming sluggish and unselective in their responses.
Stereopsis (depth perception):
the visual ability to perceive the world in three dimensions (3D) - length, width, and depth
requires the brain to detect retinal disparity
Retinal disparity:
the discrepancy (difference/inconsistency) between what the left and right eyes see
Strabismus: aka lazy eye;
eyes point different directions
If eye muscles can't keep both eyes focused in the same direction, the developing brain will lose the ability for neurons in the visual cortex to respond to input from BOTH eyes, so it'll just respond to ONE eye, causing a loss in stereoscopic depth perception
Astigmatism:
decreased responsiveness to one direction of a line or another
- Due to a not fully spherical eyeball
EX: If a child with dense cataracts on both eyes gets surgery after a few years, the child will be able to identify if objects are the same or different but won't be able to process what the visual info means
The primary visual cortex (V1) sends info to the
secondary visual cortex (area V2)
Area V2: processes info from V1 and transmits it to additional areas
- processes info from V1 and transmits it to additional areas
- Connection between V1 and V2 goes both ways
- Most cells in V2 are similar to V1 cells
- Lines, edges and sine wave gratings
V2 are more elongated cells and respond best to corners, textures and complex shapes
Areas V2 and V3 have some cells highly responsive to color and other cells highly responsive to the disparity between what the left and right eyes see
Area V4: color and curvature
Ventral stream:
visual paths in the temporal cortex that are specialized for identifying and recognizing objects
- The "what" path
- Object recognition
- Matches visual shape to internal representation
Visual Agnosia:
damage in the ventral-the absence of visual knowledge- can't identify what things are
Damage in the temporal cortex causes this
Associated agnosia: can't perceive or identify what they drew, but can draw/copy very well
Dorsal stream:
visual path in the parietal cortex that helps the motor system locate objects
- The "where" path
- Spatial location, topographical orientation, visually guided movements
Ex: Football guy passing ball and timing it correctly for the guy catching the ball
Apraxia:
damage in the dorsal-can't perform planned tasks
- Can't draw/copy pictures
People with temporal lobe damage can use vision to guide their actions, but
they cannot identify what the objects are
Inferior Temporal Cortex-
Portion of the cortex where the neurons are highly sensitive to complex aspects of the shape of visual stimuli within very large receptive fields
specialized areas for perceiving places, faces, and bodies, including bodies in motion.
Fusiform Gyrus:
brain area of the inferior temporal cortex that recognizes faces
connections between ________ and _________ strengthen the fusiform gyrus as they age
right hemisphere and part of the inferior occipital cortex aka occipital face cortex
Prosopagnosia:
impaired ability to recognize faces
- Due to damage in fusiform gyrus or not full development of the fusiform gyrus
MT (middle temporal cortex):
important for perception of visual motion
- Color insensitive
- Respond selectively when something moves at a certain speed in a certain direction
- Detects acceleration, deceleration and absolute speed
- Respond to motion in all 3 dimensions
- Gets some input directly from LGN of the thalamus
MST (medial superior temporal cortex):
responds best to complex stimuli like the expansion, contraction to rotation of visual display
MT and MST receive input mostly from the
magnocellular path: detects patterns of movement over large areas other visual field and ss color incentive
MT and MST allow us to
distinguish the result of eye movements and the result of object movements
Motion Blindness:
Impaired ability to perceive movement
- World moves in stops and starts: stop, go, stop, go; no smooth motion
- People with motion blindness are better at reaching for a moving object than at describing its motion
- Still lack and fall behind others with visual motion detection
Saccades:
voluntary eye movement
- Brain areas that monitor saccades tell area MT and parietal cortex to takes a rest since they're moving the eye muscles
- People become motion blind shortly before and during a saccade (voluntary eye movement), because of suppressed activity is area MT.
central nervous system
brain and spinal chord
peripheral nervous system
connects brain and spinal chord to rest of body's nerves outside of the brain and the spinal chord
which NS has two parts; the somatic NS and autonomic NS?
peripheral
somatic nervous system
axon conveying messages from the sense organs to peak CNS from the CNS to muscles
autonomic nervous system
controls the heart, intestine, and other organs
has some of its cell bodies within the brain and spinal cord
which NS has the sympathetic and parasympathetic nervous systems
autonomic NS
sympathetic nervous system
network of nerves that prepare organs for hard activitiy
- fight or flight
- INcreases breathing, HR, stress
- DEcreases digestion
- releases norepinephrine
sweat and adrenal gland and muscles that constrict blood vessels have sympathetic input NOT para
parasympathetic nervous system
network of nerves for vegetative, nonemergency responses
- rest and digest
- DEcreases HR
- INcreases digestion
- releases acetylcholine
- promotes sexual arousal
Which NS is aka the craniosacral system because of cranial nerves and nerves from the sacral spinal cord
parasympathetic nervous system
dorsal
toward the back
ventral
toward the stomach
anterior
toward the front end
posterior
toward the back end
superior
above another part
inferior
below another part
lateral
toward side/away from middle
medial
toward middle/away from side
proximal
located close to the point of origin/attachment
distal
located far from the point of origin/attachment