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carbamoyl phosphate synthetase I
NH4 + HCO3 + 2 ATP→ carbamoyl phosphate + 2 ADP + Pi
ornithine transcarbamoylase
carbamoyl phosphate + ornithine→ citrulline + Pi
argininosuccinate synthetase
citrulline + ATP + Asp → argininosuccinate + PPi + AMP
argininosuccinase
argininosuccinate → arginine + fumarate
arginase
arginine → urea + ornithine
