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T/F
B-lymphocytes do not require antigen to be presented by other non-lymphocyte cells.
True.
B-lymphocytes can recognize free-floating antigens directly such as viral particles, bacterial toxins, or yeast spores.
What happens in the first signal of activation of the B-lymphocytes?
Antigen binds to the BCR, resulting in the antigen cross-linking 2 BCRs.
What are the three P’s that happens when B-cells are stimulates?
Phagocytize
Processes
Present (antigen to helper t-cell)
What stabilizes the interaction of the first signal of B-cell?
CD4 of the helper T-lymphocyte binding to a MHC II of the B-lymphocyte
What happens at the second signal of the activation of B-lymphocytes?
Activated helper T-cells releases IL-4, to stimulate B-lymphocyte proliferation and differentiation.
What does the activated B-lymphocytes differentiate into?
Plasma cells and memory B-cells
What do the plasma cell produce?
antibodies
Unlike T-lymphocytes with their TCRs, memory B-lymphocytes ______ their BCRs.
retain
