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Cartilage
Flexible, avascular connective tissue with types including hyaline, elastic, and fibrocartilage, primarily composed of chondrocytes.
Bone
Dense, mineralized connective tissue that is vascular and innervated, containing a matrix rich in calcium and phosphate, with two types:compact and spongy bone.
Spongy Bone
Porous, lightweight bone found at the ends of long bones and in the core of bones, containing trabeculae and red marrow.
Compact Bone
Dense bone forming the outer layer, providing strength and containing osteons for nutrient and waste transport.
Hyaline Cartilage
Most common type of cartilage, providing support with some flexibility, found in the nose, trachea, and ends of long bones.
Elastic Cartilage
Contains more elastin fibers, found in the external ear and epiglottis, and is highly flexible.
Fibrocartilage
Contains thick collagen fibers, found in intervertebral discs and pubic symphysis, known for its durability and ability to absorb compressive forces.
Interstitial Growth
Growth from within cartilage where chondrocytes divide and secrete new matrix.
Appositional Growth
Growth at the surface of cartilage where new chondroblasts differentiate and secrete matrix on the outer edge.
Chondroblast
Immature cartilage cell that produces cartilage matrix.
Chondrocyte
Mature cartilage cell located in lacunae, maintaining the cartilage matrix.
Osteogenic Cells
Stem cells that differentiate into osteoblasts.
Osteoblast
Bone-forming cell that secretes bone matrix.
Osteocyte
Mature bone cell that maintains the bone matrix, located in lacunae.
Osteoclast
Bone-resorbing cell that breaks down bone tissue during growth, healing, and remodeling.
Skeletal System
Provides structural support, protects vital organs, allows movement, stores minerals, and houses bone marrow for blood cell production.
Cartilage Functions
Provides flexibility and support, reduces friction between bones, and absorbs shock.
Bone Functions
Provides structural support, protection, mineral storage, blood cell production, and facilitates movement.
Osteons
Cylindrical structures in compact bone for nutrient and waste transport.
Trabeculae
Honeycomb structure in spongy bone supporting red marrow.
Periosteum
Outer fibrous layer covering the bone, providing nutrients and containing osteogenic cells.
Articular Cartilage
Hyaline cartilage covering joint surfaces, reducing friction and absorbing shock.
Endosteum
Thin membrane lining the medullary cavity, involved in bone growth, repair, and remodeling.
Epiphysis
Expanded ends of a long bone containing spongy bone and red marrow.
Diaphysis
Long, cylindrical part of the bone, primarily composed of compact bone.
Epiphyseal Plate
Growth plate in children that ossifies to become the epiphyseal line in adults.
Medullary Cavity
Central cavity in the diaphysis containing yellow marrow for fat storage.
Red Marrow
Located in spongy bone, site of hematopoiesis (blood cell formation).
Yellow Marrow
Found in the medullary cavity, stores fat.
Organic Components of Bone
Collagen fibers providing tensile strength and proteoglycans aiding in resisting compressive forces.
Inorganic Components of Bone
Hydroxyapatite crystals (calcium phosphate) providing hardness and resistance to compression.
Resting Zone
Small, inactive cartilage cells in the epiphyseal plate.
Proliferation Zone
Chondrocytes undergo rapid mitosis, increasing bone length.
Hypertrophic Zone
Chondrocytes enlarge and lacunae begin to erode.
Calcification Zone
Cartilage matrix calcifies, leading to chondrocyte death.
Ossification Zone
New bone forms as osteoblasts deposit bone matrix on calcified cartilage spicules.
Bone Markings
Projections and depressions on bones that serve various functions.
Process
Prominent projection on a bone (e.g., mastoid process).
Tuberosity
Large, rounded projection on a bone (e.g., tibial tuberosity).
Spine
Sharp, slender projection on a bone (e.g., ischial spine).
Fossa
Shallow depression on a bone (e.g., iliac fossa).
Foramen
Round or oval opening in a bone (e.g., foramen magnum).
Sulcus/Groove
Furrow on a bone (e.g., intertubercular groove).
Endochondral Ossification
Process