Chapter 16

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34 Terms

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Acquired Immunity
antibodies are produced within the person and it is long lasting protection

two types: natural and artificial
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Agammaglobulinemia
an inherited disorder in which patients lack ability to produce antibodies
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Allergen
a substance that causes an allergic response
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Anaphylaxis
results from the release of chemical mediators from basophils
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Antigen-antibody complex
an antibody combined with an antigen and is capable of activating the complement cascade
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Antigen
foreign organic substances that stimulate the production of antibodies
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Attenuated Vaccine
made with a pathogen that been weakened or made harmless
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B cells
function to produce antibodies against antigens
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Cell mediated immunity
involves a variety of cell types, with antibodies playing only a minor role, if any
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Conjugate vaccine
vaccine in which combines a weak antigen with a strong antigen
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Delayed type hypersensitivity reactions
* also known as type IV
* part of cell mediated immunity
* prime mode of defense against intracellular bacteria and fungi
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DNA vaccine
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Humoral Immunity
glycoproteins called antibodies are produced by B cells to destroy specific microbes
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Hybridoma
made by combining a single plasma cell and a rapidly dividing tumor cell
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Hypersensitivity Reactions
overly sensitive or reactive immune system
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Immediate type hypersensitivity reactions
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Immunity
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Immunosupressed person
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Immunocompetent person
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Immunodiagnostic procedures
detects either antigens or antibodies in clincial specimens
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Immunoglobulins
* antibodies are a class of glycoproteins
* There are five types: IgA, IgD, IgE, IgG, IgM
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Immunology
scientific study of the immune system and immune responses
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Inactivated vaccine
made with a pathogen that has been killed and is less effective than live vaccines
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Monoclonal antibodies
* large amounts of specific antibodies produced by hybridomas
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Natural Killer (NK) cell
* lack typical T or B cell surface markers
* kill target cells
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Plasma cell
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Primary response
* the initial immune response to an antigen


* some b cells become memory cells
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Regulatory T cells
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Secondary response
increased production of antibodies following the second exposure to a particular antigen
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T cells
3 categories of T cells:


1. helper
2. cytotoxic
3. regulatory
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T-dependent antigens
T cells are required in their processing
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T-independent antigens
the processing of these requires only B cells
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Toxoid vaccine
made from a toxin that has been made harmless
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Vaccine
a material that can artificially induce immunity