Cell Division and Mitosis Overview

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77 Terms

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Cell Division

Process by which a parent cell divides into two daughter cells.

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Eukaryotic Chromosomes

Structures made of DNA and proteins in eukaryotic cells.

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Cell Cycle

Life cycle of a cell from formation to division.

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Mitosis

Nuclear division resulting in genetically identical daughter cells.

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Meiosis

Cell division producing gametes with half chromosome number.

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Asexual Reproduction

Reproduction involving a single organism, like Amoeba.

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Binary Fission

Type of cell division in prokaryotes and unicellular eukaryotes.

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Zygote

Fertilized egg that develops into a multicellular organism.

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Cell Cycle Control System

Regulatory system ensuring proper cell cycle progression.

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Checkpoint Proteins

Proteins that monitor and regulate the cell cycle.

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Genome

Complete set of genetic information in a cell.

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Karyotype

Visual representation of an organism's complete set of chromosomes.

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Somatic Cells

All body cells except reproductive cells, containing 46 chromosomes.

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Gametes

Reproductive cells (sperm and egg) with 23 chromosomes.

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Ploidy

Number of sets of chromosomes in a cell.

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Diploid

Cells with two sets of chromosomes (2n), like humans.

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Haploid

Cells with one set of chromosomes (n), like gametes.

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Homologous Chromosomes

Chromosome pairs with similar structure and genetic content.

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Chromatin

Complex of DNA and proteins forming chromosomes.

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Histone Proteins

Proteins that help package DNA into chromatin.

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Chromosome Structure

Linear DNA molecule associated with proteins.

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Cellular Organization

Arrangement of genetic material within a cell.

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Eukaryotic Cell Size

Typical size ranges from 10 to 100 µm.

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DNA Length in Cells

Human cell DNA length is about 2 meters.

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Autosomes

Non-sex chromosomes; humans have 22 pairs.

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Sex Chromosomes

Chromosomes determining sex; XX or XY in humans.

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Cell Division Regulation

Highly regulated series of events in cell division.

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Mitotic Spindle

Structure that separates chromosomes during mitosis.

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Nucleosome

DNA wrapped around histones forming a unit.

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Linker DNA

Connects nucleosomes like beads on a string.

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10-nm fiber

Initial DNA structure formed by nucleosomes.

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30-nm fiber

Thicker fiber formed by coiled nucleosomes.

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300-nm fiber

Formed by looped domains attached to nuclear matrix.

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Metaphase chromosome

Highly condensed chromosome during cell division.

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Sister chromatids

Identical copies of a replicated chromosome.

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Centromere

Region where sister chromatids are joined.

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Cohesins

Proteins that hold sister chromatids together.

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Eukaryotic cell cycle

Sequence from cell formation to division.

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Interphase

Phase where cell grows and DNA replicates.

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Mitotic phase

Shortest phase involving mitosis and cytokinesis.

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G1 phase

First growth phase, lasts 8-10 hours.

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S phase

DNA synthesis phase, lasts 6-8 hours.

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G2 phase

Second growth phase, lasts 4-6 hours.

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Cytokinesis

Division of cytoplasm and its contents.

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Prophase

Chromosomes condense and spindle begins to form.

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Prometaphase

Nuclear envelope fragments, spindle fibers attach.

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Metaphase

Chromosomes align at the metaphase plate.

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Anaphase

Sister chromatids separate and move apart.

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Telophase

Nuclear membranes reform around separated chromosomes.

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Chromosome duplication

Process of replicating chromosomes before division.

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Radial loop domains

300-nm fiber loops attached to nuclear matrix.

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Cell checkpoint

Regulatory point ensuring cell cycle progression.

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Chromosome arm

Part of a chromosome extending from the centromere.

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Nuclear matrix

Framework providing structure within the nucleus.

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Duplicated chromosomes

Chromosomes that have undergone replication.

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Cohesin Proteins

Proteins that hold sister chromatids together.

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Kinetochore Microtubules

Microtubules that attach to chromatids during mitosis.

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Polar Microtubules

Nonkinetochore microtubules that push cell poles apart.

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Cleavage Furrow

Indentation indicating cytokinesis in animal cells.

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Cell Plate

Structure forming between plant daughter cells during cytokinesis.

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Somatic Cell Division

Produces two genetically identical daughter cells.

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Centrosome

Microtubule organizing center defining spindle poles.

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Aster

Radial array of microtubules from centrosome.

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Metaphase Plate

Equatorial plane where chromosomes align during metaphase.

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G1 Checkpoint

Control point assessing cell readiness to divide.

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G0 Phase

Nondividing state for cells not receiving division signals.

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Cyclins

Proteins regulating cell cycle checkpoints.

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Cyclin-Dependent Kinases

Enzymes activated by cyclins to regulate cell cycle.

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Cancer

Disease caused by uncontrolled cell cycle regulation.

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Benign Tumor

Non-invasive tumor remaining at original site.

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Malignant Tumor

Tumor that invades surrounding tissues and metastasizes.

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Metastasis

Spread of cancer cells to distant body parts.

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Checkpoints

Control points regulating cell cycle events.

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M Phase

Phase of mitosis where cell divides.

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S Phase

Phase where DNA is replicated.

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G2 Phase

Phase preparing cell for mitosis.

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Cytoplasmic Division

Process of dividing the cytoplasm during cytokinesis.