HIV-1 - Regulatory and Accessory Proteins

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Last updated 6:25 AM on 7/13/26

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1

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Tat

Transcriptional activator

2

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Rev

Promotes transport of unspliced mRNAs (messenger RNA)

3

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Nef

Downregulation of cellular CD4 and MHC 1 proteins

4

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Vpu

Facilitates virus assembly and release

5

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Vpr

Facilitates nuclear entry in non dividing cells

6

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Vif

Increases viral infectivity in central cell types