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100 vocabulary flashcards covering bacteria and microbiology concepts typical of microbiology lectures.
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Bacteria
Single-celled prokaryotic microorganisms; range from harmless to pathogenic and many are beneficial.
Prokaryote
An organism lacking a nucleus; includes bacteria and archaea.
Eukaryote
Organism with a nucleus and membrane-bound organelles.
Archaea
A domain of single-celled prokaryotes distinct from bacteria, often found in extreme environments.
Gram-positive
Bacteria with a thick peptidoglycan layer that retain crystal violet stain (purple under Gram stain).
Gram-negative
Bacteria with a thin peptidoglycan layer and outer membrane; counterstain pink/red.
Cocci
Spherical-shaped bacteria.
Bacilli
Rod-shaped bacteria.
Spirilla
Spiral-shaped bacteria with rigid bodies.
Spirochetes
Long, flexible spiral bacteria.
Escherichia coli
Common gut bacterium; model organism; some strains are pathogenic.
Staphylococcus aureus
Gram-positive cocci in clusters; can cause skin infections and MRSA.
Staphylococcus epidermidis
Skin commensal; often an opportunistic pathogen in hospitals.
Streptococcus pneumoniae
Gram-positive diplococcus; causes pneumonia and meningitis.
Streptococcus pyogenes
Group A strep; causes strep throat and other infections.
Bacillus subtilis
Gram-positive rod; soil bacterium; model organism; forms endospores.
Bacillus cereus
Bacterium that can cause food poisoning.
Salmonella enterica
Gram-negative rod; causes gastroenteritis and typhoid fever.
Shigella dysenteriae
Causes shigellosis; highly infectious Gram-negative rod.
Campylobacter jejuni
Curved Gram-negative rod; leading cause of bacterial gastroenteritis.
Vibrio cholerae
Curved Gram-negative rod; causes cholera through a toxin.
Helicobacter pylori
Curved Gram-negative rod; colonizes the stomach; linked to ulcers.
Listeria monocytogenes
Gram-positive rod; foodborne pathogen; can cause listeriosis.
Clostridioides difficile
Anaerobic, spore-forming bacterium; causes antibiotic-associated diarrhea.
Clostridium botulinum
Produces botulinum toxin; causes botulism; anaerobic spore-former.
Clostridium tetani
Causes tetanus; anaerobic spore-former.
Pseudomonas aeruginosa
Gram-negative rod; opportunistic pathogen; highly resistant and versatile.
Klebsiella pneumoniae
Gram-negative rod; pneumonia and other infections; often antibiotic resistant.
Enterococcus faecalis
Gram-positive cocci; normal gut flora; can cause nosocomial infections.
Neisseria meningitidis
Gram-negative diplococcus; causes meningitis and sepsis.
Neisseria gonorrhoeae
Gram-negative diplococcus; causative agent of gonorrhea.
Mycobacterium tuberculosis
Acid-fast rod; etiological agent of tuberculosis.
Mycobacterium leprae
Cause of leprosy; grows slowly in host tissues.
Chlamydia trachomatis
Obligate intracellular pathogen; causes chlamydia and trachoma.
Rickettsia rickettsii
Obligate intracellular bacterium; causes Rocky Mountain spotted fever.
Borrelia burgdorferi
Spirochete; causes Lyme disease.
Treponema pallidum
Spirochete; causes syphilis.
Streptomyces coelicolor
Soil actinobacterium; known for antibiotic production; model organism for Streptomycetes.
Lactobacillus acidophilus
Lactic acid bacterium; probiotic; common in yogurt.
Bifidobacterium bifidum
Probiotic gut bacterium; part of healthy microbiota.
Saccharomyces cerevisiae
Baker's yeast; model eukaryotic organism; used in baking and fermentation.
Saccharomyces boulardii
Probiotic yeast marketed for gut health.
Staphylococcus aureus MRSA
Methicillin-resistant Staphylococcus aureus; antibiotic-resistant pathogen.
Escherichia coli K-12
Non-pathogenic lab strain used for teaching and research.
Bacillus anthracis
Causes anthrax; spore-forming Gram-positive rod; highly dangerous.
Streptococcus mutans
Oral bacterium linked to dental caries.
Streptococcus thermophilus
Used in dairy fermentation; contributes to yogurt cultures.
Actinobacteria
Phylum of high G+C Gram-positive bacteria including many soil microbes and pathogens.
Firmicutes
Phylum of Gram-positive bacteria; includes Bacillus, Clostridium, Streptococcus.
Proteobacteria
Major phylum of Gram-negative bacteria; includes many pathogens.
Cyanobacteria
Photosynthetic bacteria that release oxygen; important in early Earth and modern ecosystems.
Gram stain
Differential staining method to classify bacteria as Gram-positive or Gram-negative.
Peptidoglycan
Polymer forming bacterial cell walls; thick in Gram-positive bacteria.
Capsule
Gelatinous outer layer aiding immune evasion and adherence.
Flagellum
Whip-like structure enabling bacterial motility.
Pili
Hair-like appendages for attachment and DNA transfer.
Biofilm
Structured community of microbes attached to a surface; often resistant to treatment.
Oxidase test
Chemical test to detect certain cytochrome oxidases in bacteria.
Catalase test
Test for the enzyme catalase; bubbles form with hydrogen peroxide if positive.
Antisepsis
Reduction of pathogens on living tissue to prevent infection.
Antibiotic resistance
Bacteria's ability to survive exposure to antibiotics.
Quorum sensing
Cell-density–dependent communication that regulates gene expression.
Probiotic
Live microorganisms that confer a health benefit when consumed.
Bacteriophage
Virus that infects and replicates within bacteria.
Antibiotic
Substance that kills or inhibits growth of bacteria.
Sterilization
Process that destroys all forms of life, including spores.
Disinfection
Reduces viable microorganisms on inanimate objects; may not kill spores.
Pathogen
Microorganism capable of causing disease.
Opportunistic pathogen
Causes disease mainly in hosts with weakened defenses.
Anaerobe
Organism that does not require oxygen for growth; may be harmed by oxygen.
Aerobe
Organism that requires oxygen for growth.
Facultative anaerobe
Can grow with or without oxygen, adapting to different environments.
Endospore
Dormant, highly resistant structure formed by some bacteria to survive harsh conditions.
Sporulation
Process of endospore formation in certain bacteria.
Model organism
A species used widely in research to understand biology, e.g., E. coli, S. cerevisiae.
Culture medium
Substance providing nutrients for microbial growth; can be solid or liquid.
Growth medium
Medium used to cultivate microorganisms; often contains nutrients and minerals.
Gram staining procedure
Four-step process: stain with crystal violet, apply iodine, decolorize, counterstain.
Culture
Growth of microorganisms in a controlled environment.
Microbiome
Community of microorganisms living in a specific environment, such as the gut.
Fermentation
Metabolic process producing energy without oxygen; used in food production.
Pathogenicity
Ability of a organism to cause disease.
Virulence factor
Molecule that enables a pathogen to cause disease.
Biohazard
Biological substance presenting a risk to health.
Petri dish
Flat dish used to culture microorganisms on solid media.
Colony
Visible group of identical microbes arising from a single cell.
Aseptic technique
Procedures to prevent contamination of sterile materials.
Sterile
Free from all living microorganisms.
Contamination
Unwanted introduction of microbes into an environment or sample.
Agar
Gelatinous substance used to solidify growth media in plates.
Nutrient broth
Liquid medium providing nutrients for microbial growth.
Koch's postulates
Historical criteria linking a microbe to a disease.
Pasteurization
Mild heating to reduce pathogens and extend shelf life.
Autoclave
Device that sterilizes using pressurized steam.
Incubation
Maintaining suitable conditions for microbial growth.
Colony-forming unit
Unit estimating viable bacteria by counting colonies.
Nutrient agar
Solid growth medium made with agar and nutrients.
Obligate intracellular parasite
Organism that can only replicate inside host cells.
Gram-variable
Bacteria displaying inconsistent Gram staining results.
Mesophile
Organism that grows best at moderate temperatures (roughly 20–45°C).