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what are the 6 important parts of the female reproductive tract
Broad ligament, ovary, oviduct, uterus, vagina, and vulva
where does a fertilized egg implant in a litter bearing species reproductive tract
the uterine horn
What does the cervix separate
the uterus and the vagina
what is a sling like structure that suspends the reproductive tract in the abdominal cavity
The broad ligament
What does the mesovarian part of the broad ligament attach ?
it attaches the broad ligament to the overy
what does the mesosalpinx part of the broad ligament attach
the broad ligament to the oviduct
What does the mesometrium part of the broad ligament attach
the broad ligament to the uterus and stretches as the fetus grows
What is the largest part of the broad ligament
mesometrium
What is the broad ligament
a thin sheet of connective tissue that covers the ovaries, uterus, and oviducts, stabilizing their position and anchoring them to the walls and floor of the pelvic cavity.
what is the function of the broad ligament
as support
what are the two regions of the ovary
the cortex and medulla
Where is the cortex part of the ovary located
on the peripheral region
What part of the ovary are follicles housed
the cortex
Where is the medulla located in the ovary
in the central region
what is located in the medulla
numerous blood vessels
what is the exocrine function of the ovary
to produce cells
what is the endocrine function ovary
to produce estrogen and progesterone
what are the two cycles that the ovary experiences
the estrous cycle and the menstrual cycle
what is the estrous cycle
the limited period of time when females are sexually receptive to males
What is the menstrual cycle
the period of the beginning of one menstrua to the next; not including the “ period”
what is folliculogenesis
the development of primordial follicles to their final stage
what is the tunica Albuginea
a supporting connective tissue surrounding follicles
what is the stroma in the ovary
connective tissue surrounding follicles
what are the 8 phases of a primordial follicle to corpus albicans
Primordial follicles, primary follicle, secondary follicle, Developing antral ( tertiary) follicle, Antral ( dominant) follicle, ovulating follicle, Corpus Luteum, and Corpus Albicans
when are the primordial follicles created
when the fetus is developed
what type of cells surround the primordial follicle
squamous epithelial cells
True or False: Cause of stimulation of the development of the primordial follicle is unknown
True
what is the primary follicle made up of/ is
it is an oocyte surrounded by a single layer of cuboidal granulosa cells
what type of cells surrounds the secondary follicle
cuboidal granulosa cells
What is the difference between the primordial follicle and the primary follicle
the type of surrounding cells
What is the difference between the primary follicle and secondary follicle
the secondary follicle has more than one layer of cuboidal granulosa cells
what are the changes that appear when the tertiary follicle forms
an antrum begins to form and is filled with follicular fluid, there is an increase in follicular size and smaller pockets of follicular fluid are formed
What produces the follicular fluid
the granulosal cells
what occurs in the Graafian ( dominant ) follicle
the antrum is fully formed, the follicle is large enough to be palpated and the wall of the follicle thins and the egg eventually erupts.
what causes the thinning of the follicular wall
an enzyme that erodes the wall
what connects the granulosal cells
gap junctions
what does the gap junction and finger like projections of granulosa cells do
communicate between cells and communicate with the oocyte
what is the 1st oocyte protein discovered
Growth Differentiation Factor 9 ( GDF-9)
what does the GDF-9 do
directs the oocyte growth
What happens to animals when the GDF-9 is knock out in animals
the follicles cease developing at the primary follicle stage
what are the cumulus cells
granulosa cells withing the cumulus oophorous region, these cells hang tightly to the oocyte even after ovulation
what are the cumulus oophorous
an entire region of cells surrounding the oocytes
what are the two parts of the Theca
the theca interna and theca externa
what separates the theca and the rest of the follicle
a basement membrane
what is one difference between the theca interna and theca externa
the theca interna has blood vessels and capillaries, the theca externa do not
Does the theca interna secrete hormones?
yes
what hormones does the theca interna produce
testosterone
what are the 5 parts of the Oocyte anatomy
Nucleus, Corona Radiata, Zona Pellucida, Vitellus, and Vitelline membrane
what is the vitelline membrane
the cell membrane of the ovulated egg
what is the vitellus
the cytoplasm of an oocyte
what is the zona Pellucida
an area in the oocyte that protects its oocyte
what is the zona pellucida made up of
a protein triplet
what is the purpose of the Zona Pellucida
to regulate which sperm fertilizes the oocyte
what is the Corona Radiata
an single layer of cells that surround the oocyte; these are the cumulus cells that are still attached to the oocyte once ovulation occurred
What is recruitment in folliculogenesis
a group/cohort of follicles that begin to grow
what is an atretic in folliculogenesis
the death of a follicle
what hormone that when present stops follicles from ovulating
progestogen
where does the Progestogen in the folliculogenesis come from
the previous estrus cycles Corpus Luteum
what is luteolysis
the functional and structural degradation of the corpus luteum
what hormone allows follicles to ovulate
The luteinizing hormone
What phases does the follicle go through in folliculogenesis
from recruitment to selected to dominant to either ovulation or atretic
About how many follicles ovulate in female humans until menopause
about 400
What is follicular atresia
the degeneration that a follicle undergoes if not ovulated
what type of follicles does follicular atresia mostly occur in
primay, secondary, tertiary and Graafian follicles
What are the glands involved in the hormonal secretion during the estrous cycle
the hypothalamus, Anterior pituitary gland, Posterior pituitary gland, and the gonadial axis
What is the hormonal secretion during the recruitment part of the estrous cycle
the growing small follicles secretes estrogen which goes to the hypothalamus, it then signals GRNH to stimulate the anterior pituitary gland and the posterior pituitary gland to release a lot of Follicle stimulating hormone and a small amount of Luteinizing hormone
What is the hormonal secretion during the selection part of the estrous cycle
the now medium follicles secrete more estrogen to the hypothalamus, it then signals GRNH to stimulate the anterior pituitary gland and the posterior pituitary gland to release a smaller amount of follicle stimulating hormone and a larger amount of luteinizing hormone
What is the hormonal secretion during the dominance part of the estrous cycle
the dominant follicle releases a larger amount of estrogen to the hypothalamus, it signals GRNH to stimulate the anterior pituitary gland and the posterior pituitary gland to release a smaller amount of follicle stimulating hormone and a larger amount of luteinizing hormone
what is the luteinizing hormone
a hormone produces by gonadotrophic cells in the anterior pituitary gland
what hormone triggers ovulation and development of the corpus luteum
the luteinizing hormone
what is the definition of ovulation
the purposeful degradation of tissue
FITB: Ovulation is instead due to _____ digestion of the preovulatory follicular wall
enzymatic
what is the place in the ovary where the preovulatory follicular wall starts to digest called
stigma
what are 6 anatomical changes associated with ovulation
increased follicle diameter, dissociation of granulosa cells, granulosa begins to luteinize, oocyte becomes free floating, stigma formation, the basement membrane begins to breakdown
When does meiosis resume of the oocyte
after puberty starts
How many daughter cells are viable in oogenesis and how many are polar bodies
1 is viable and the other 3 are polar bodies
what is the first 2n cell made after egg fertilization
zygote
What is induced ovulation
ovulation where mating is necessary for ovulation to occue
what animals have induced ovulation
rabbits, camels, and cats
what is spontaneous ovulation
ovulation that occurs whether the animal is mated or not
what animals have spontaneous ovulation
humans and livestock
what are the 4 parts of angiogenesis
the basement membrane breaks down, proliferation of capillary endothelial cells, endothelial cell migration and the formation of capillaries from these cells
what is angiogenesis
the creation of new blood vessels very rapidly
other than after ovulation where is angiogenesis present
in tumor formation
what are the 3 stages for Luteal formation
Corpus hemorragicum, Corpus Luteum, and Corpus albicans
what is the corpus hemorragicum
the blood filled remains of a ruptured follicle
True or False: There is a lot of Progestogen production in the Corpus Hemorragicum
false, there is little
What is another name for the Corpus Luteum
yellow body
what is the Corpus Luteum
the formed tissue from the ruptured follicle
True or False: There is a increase production of progestogen in the corpus luteum
true
what is another word from corpus albicans
white body
what is the corpus albicans
a regressed form of the corpus luteum
when does the corpus albicans formed
in the absence of pregnancy
Is there a large or smaller production of progestogen in the corpus albicans
smaller
what are the small luteal cells formed from
theca cells
what are large luteal cells formed from
granulosa cells
what hormone does the granulosa cells release
estrogen
what hormone does the theca cells produce
testosterone
what type of hormones are FSH and LH
gonadotrophins
what hormone stays up once pregnancy occurs
progesterone